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Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody

Details for Product No. ABIN955037, Supplier: Log in to see
Antigen
  • CG10716
  • CG18615
  • CG31136
  • CG5448
  • CT30033
  • Dm Syx1
  • DmSyx1A
  • Dmel\\CG31136
  • SYX1A
  • Syt1A
  • Syx
  • Syx-1A
  • Syx1
  • Syx1a
  • SyxA
  • anon-EST:Gibbs4
  • anon-WO02059370.54
  • dSyx1
  • l(3)06737
  • synt
  • syt-1A
  • syx
  • syx-1
  • syx-1A
  • syx1
  • syx1A
  • STX1A
  • hpc-1
  • p35-1
  • stx1
  • sx1a
  • syntaxin1a
  • HPC-1
  • P35-1
  • STX1
  • SYN1A
Epitope
AA 36-65, N-Term
45
15
13
12
10
7
3
3
2
2
2
2
1
1
1
1
1
Reactivity
Human
105
53
53
12
6
2
2
2
1
1
1
1
Host
Rabbit
95
16
4
2
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
84
34
33
25
16
15
13
9
8
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 36~65 amino acids from the N-terminal region of Human STX1A Genename: STX1A
Isotype Ig
Specificity This antibody recognizes Human Syntaxin 1A / STX1A (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name Syntaxin 1A / STX1A (STX1A Antibody Abstract)
Background This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.Synonyms: Neuron-specific antigen HPC-1, STX1, Syntaxin-1A
Molecular Weight 33023 Da
Gene ID 6804
NCBI Accession NP_001159375
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody (ABIN955037) Flow cytometric analysis of 293 cells using Syntaxin 1A / STX1A Antibody (N-term) Cat...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody (ABIN955037) Formalin fixed, paraffin embedded skeletal muscle stained with Syntaxin 1A / STX1A An...
Western Blotting (WB) image for anti-Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody (ABIN955037) Western blot analysis of Syntaxin 1A / STX1A Antibody (N-term) in 293 cell line lysat...
Background publications Yoshida, Kato, Yokoi et al.: "Association of genetic variants with chronic kidney disease in individuals with different lipid profiles." in: International journal of molecular medicine, Vol. 24, Issue 2, pp. 233-46, 2009 (PubMed).

Hamdan, Piton, Gauthier et al.: "De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy." in: Annals of neurology, Vol. 65, Issue 6, pp. 748-53, 2009 (PubMed).

Corominas, Ribasés, Cuenca-León et al.: "Contribution of syntaxin 1A to the genetic susceptibility to migraine: a case-control association study in the Spanish population." in: Neuroscience letters, Vol. 455, Issue 2, pp. 105-9, 2009 (PubMed).

Chen, Nelson, Khauv et al.: "Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis." in: The Journal of biological chemistry, Vol. 284, Issue 11, pp. 6877-84, 2009 (PubMed).

Ramakrishnan, Drescher, Drescher: "Direct interaction of otoferlin with syntaxin 1A, SNAP-25, and the L-type voltage-gated calcium channel Cav1.3." in: The Journal of biological chemistry, Vol. 284, Issue 3, pp. 1364-72, 2009 (PubMed).

Tian, Das, Sheng: "Ca2+-dependent phosphorylation of syntaxin-1A by the death-associated protein (DAP) kinase regulates its interaction with Munc18." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 26265-74, 2003 (PubMed).