Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody

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Antigen
  • CG10716
  • CG18615
  • CG31136
  • CG5448
  • CT30033
  • Dm Syx1
  • DmSyx1A
  • Dmel\\CG31136
  • SYX1A
  • Syt1A
  • Syx
  • Syx-1A
  • Syx1
  • Syx1a
  • SyxA
  • anon-EST:Gibbs4
  • anon-WO02059370.54
  • dSyx1
  • l(3)06737
  • synt
  • syt-1A
  • syx
  • syx-1
  • syx-1A
  • syx1
  • syx1A
  • STX1A
  • hpc-1
  • p35-1
  • stx1
  • sx1a
  • syntaxin1a
  • HPC-1
  • P35-1
  • STX1
  • SYN1A
  • Syntaxin 1A
  • syntaxin-1A-like
  • syntaxin 1A (brain)
  • syntaxin-1A
  • Syx1A
  • LOC100061863
  • STX1A
  • stx1a
  • EDI_005240
  • Tsp_07354
  • Stx1a
  • LOC100512594
  • LOC100855965
Alternatives
anti-Human Syntaxin 1A (Brain) antibody for ELISA
Epitope
AA 36-65, N-Term
44
15
10
10
10
10
8
7
3
2
2
2
2
2
1
1
1
1
Reactivity
Human
147
84
72
24
22
18
13
7
4
3
3
2
2
2
1
1
1
1
1
Host
Rabbit
106
44
6
2
Clonality
Polyclonal
Conjugate
Un-conjugated
5
5
5
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
119
59
53
36
19
17
14
14
11
5
3
1
1
Options
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Immunogen KLH conjugated synthetic peptide between 36~65 amino acids from the N-terminal region of Human STX1A Genename: STX1A
Isotype Ig
Specificity This antibody recognizes Human Syntaxin 1A / STX1A (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name Syntaxin 1A / STX1A (STX1A Antibody Abstract)
Background This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.Synonyms: Neuron-specific antigen HPC-1, STX1, Syntaxin-1A
Molecular Weight 33023 Da
Gene ID 6804
NCBI Accession NP_001159375
Pathways Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody (ABIN955037) Flow cytometric analysis of 293 cells using Syntaxin 1A / STX1A Antibody (N-term) Cat...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody (ABIN955037) Formalin fixed, paraffin embedded skeletal muscle stained with Syntaxin 1A / STX1A An...
Western Blotting (WB) image for anti-Syntaxin 1A (Brain) (STX1A) (AA 36-65), (N-Term) antibody (ABIN955037) Western blot analysis of Syntaxin 1A / STX1A Antibody (N-term) in 293 cell line lysat...
Background publications Hamdan, Piton, Gauthier, Lortie, Dubeau, Dobrzeniecka, Spiegelman, Noreau, Pellerin, Côté, Henrion, Fombonne, Mottron, Marineau, Drapeau, Lafrenière, Lacaille, Rouleau, Michaud: "De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy." in: Annals of neurology, Vol. 65, Issue 6, pp. 748-53, 2009 (PubMed).

Corominas, Ribasés, Cuenca-León, Narberhaus, Serra, del Toro, Roig, Fernández-Fernández, Macaya, Cormand: "Contribution of syntaxin 1A to the genetic susceptibility to migraine: a case-control association study in the Spanish population." in: Neuroscience letters, Vol. 455, Issue 2, pp. 105-9, 2009 (PubMed).

Chen, Nelson, Khauv, Bennett, Radisky, Hirai, Bissell, Radisky: "Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis." in: The Journal of biological chemistry, Vol. 284, Issue 11, pp. 6877-84, 2009 (PubMed).

Ramakrishnan, Drescher, Drescher: "Direct interaction of otoferlin with syntaxin 1A, SNAP-25, and the L-type voltage-gated calcium channel Cav1.3." in: The Journal of biological chemistry, Vol. 284, Issue 3, pp. 1364-72, 2009 (PubMed).

Yoshida, Kato, Yokoi, Oguri, Watanabe, Metoki, Yoshida, Satoh, Aoyagi, Nishigaki, Nozawa, Yamada: "Association of genetic variants with chronic kidney disease in individuals with different lipid profiles." in: International journal of molecular medicine, Vol. 24, Issue 2, pp. 233-46, 2009 (PubMed).

Tian, Das, Sheng: "Ca2+-dependent phosphorylation of syntaxin-1A by the death-associated protein (DAP) kinase regulates its interaction with Munc18." in: The Journal of biological chemistry, Vol. 278, Issue 28, pp. 26265-74, 2003 (PubMed).