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Syndecan Binding Protein (Syntenin) 2 (SDCBP2) (AA 12-42), (N-Term) antibody

Details for Product No. ABIN955044, Supplier: Log in to see
Antigen
  • SITAC
  • SITAC18
  • ST-2
Epitope
N-Term, AA 12-42
18
15
12
3
2
2
2
Reactivity
Human
54
11
10
2
1
1
1
Host
Rabbit
34
15
6
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
3
3
3
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
37
35
17
3
2
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 12-42 amino acids from the N-terminal region of Human SDCBP2 (NP_536737.3, NP_056500.2) Genename: SDCBP2
Isotype Ig
Specificity Recognizes SDCBP2 (N-term).
Purification Protein A column followed by peptide Affinity purification
Alternative Name Syntenin-2 / SDCBP2 (SDCBP2 Antibody Abstract)
Background Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans. Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization. Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors.Synonyms: SITAC18, Syndecan-binding protein 2
Gene ID 27111
NCBI Accession NP_001186713
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Syndecan Binding Protein (Syntenin) 2 (SDCBP2) (AA 12-42), (N-Term) antibody (ABIN955044) Western blot analysis of SDCBP2 Antibody (N-term) Cat.-No AP53822PU-N in HL-60 cell l...
Background publications Wang, Yoon, Oh et al.: "Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags." in: Biochemical and biophysical research communications, Vol. 345, Issue 3, pp. 1022-32, 2006 (PubMed).

Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Koroll, Rathjen, Volkmer: "The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity." in: The Journal of biological chemistry, Vol. 276, Issue 14, pp. 10646-54, 2001 (PubMed).

Borrell-Pagès, Fernández-Larrea, Borroto et al.: "The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein." in: Molecular biology of the cell, Vol. 11, Issue 12, pp. 4217-25, 2000 (PubMed).