SNTB2 antibody (Middle Region)

Catalog No. ABIN955046

Product Details anti-SNTB2 Antibody

Target: SNTB2 (Syntrophin, beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2) (SNTB2))

Binding Specificity: AA 216-245, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNTB2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects human Syntrophin-3 / SNTB2.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column,; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 216-245aa) of human Syntrophin-3 / SNTB2.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SNTB2

Target: SNTB2 (Syntrophin, beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2) (SNTB2))

Alternative Name: Syntrophin-3 / SNTB2 (SNTB2 Products)

Synonyms: Snt2 antibody, D16S2531E antibody, EST25263 antibody, SNT2B2 antibody, SNT3 antibody, SNTL antibody, syntrophin, basic 2 antibody, syntrophin beta 2 antibody, Sntb2 antibody, SNTB2 antibody

Background: Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.Synonyms: 59 kDa dystrophin-associated protein A1 basic component 2, Beta-2-syntrophin, SNT2B2, SNT3, SNTL, Syntrophin-like

Gene ID: 6645

NCBI Accession: NP_006741