TBC1 Domain Family, Member 22A (TBC1D22A) (C-Term), (AA 329-358) antibody

Details for Product No. ABIN955093
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Antigen
Synonyms C22orf4, HSC79E021, BC023106, D15Ertd781e, RGD1306588
Epitope
C-Term, AA 329-358
(7), (6), (3), (2), (1)
Reactivity
Human
(15), (3), (3)
Host
Rabbit
(15)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(15), (8), (8), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN955093
357.50 $
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Immunogen KLH conjugated synthetic peptide between 329-358 amino acids from the C-terminal region of human PUS1
Specificity This antibody reacts to PUS1.
Purification Affinity chromatography on Protein A
Alternative Name TBC1D22A
Background This gene encodes a pseudouridine synthase that converts uridine to pseudouridine once it has been incorporated into an RNA molecule. The encoded enzyme may play an essential role in tRNA function and in stabilizing the secondary and tertiary structure of many RNAs. A mutation in this gene has been linked to mitochondrial myopathy and sideroblastic anemia. Alternate splicing results in multiple transcript variants.
Alternate names: C22orf4, TBC1 domain family member 22A
Gene ID 25771
NCBI Accession NP_055161
Research Area Signaling
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Fernandez-Vizarra, Berardinelli, Valente et al.: "Nonsense mutation in pseudouridylate synthase 1 (PUS1) in two brothers affected by myopathy, lactic acidosis and sideroblastic anaemia (MLASA)." in: Journal of medical genetics, Vol. 44, Issue 3, pp. 173-80, 2007 (PubMed).

Sugiyama, Masuda, Shinoda et al.: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, 2007 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Demling: "Burns: what are the pharmacological treatment options?" in: Expert opinion on pharmacotherapy, Vol. 9, Issue 11, pp. 1895-908, 2008 (PubMed).

Bergmann, Campagna, McLoughlin et al.: "Systematic molecular genetic analysis of congenital sideroblastic anemia: evidence for genetic heterogeneity and identification of novel mutations." in: Pediatric blood & cancer, Vol. 54, Issue 2, pp. 273-8, 2009 (PubMed).

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