TCEB1 antibody (C-Term)

Catalog No. ABIN955124

Product Details anti-TCEB1 Antibody

Target: TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))

Binding Specificity: AA 68-98, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEB1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detectsTCEB1 (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity Purified

Immunogen: KLH conjugated synthetic peptide between 68-98 amino acids from the C-terminal region of human TCEB1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TCEB1

Target: TCEB1 (Transcription Elongation Factor B (SIII), Polypeptide 1 (15kDa, Elongin C) (TCEB1))

Alternative Name: TCEB1 (TCEB1 Products)

Synonyms: 2610043E24Rik antibody, 2610301I15Rik antibody, AA407206 antibody, AI987979 antibody, AW049146 antibody, SIII antibody, eloC antibody, TCEB1 antibody, fb09f09 antibody, wu:fb09f09 antibody, zgc:111990 antibody, zgc:92635 antibody, elongin C antibody, elongin C L homeolog antibody, transcription elongation factor B (SIII), polypeptide 1b antibody, Eloc antibody, eloc.L antibody, ELOC antibody, tceb1b antibody

Background: This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.Synonyms: El °C, Elongin 15 kDa subunit, Elongin C, Elongin-C, RNA polymerase II transcription factor SIII subunit C, Transcription elongation factor B polypeptide 1

Gene ID: 6921

NCBI Accession: NP_001191786

Pathways: SARS-CoV-2 Protein Interactome