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Transcription Factor A, Mitochondrial (TFAM) (AA 223-254), (C-Term) antibody

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Synonyms tcf6, mttf1, mttfa, tcf6l1, tcf6l2, tcf6l3, mttfa-A, xl-mtTFA, MGC153358, zgc:153358, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3, AI661103, Hmgts, mtTFA, tsHMG, Mttfa
AA 223-254, C-Term
(24), (15), (10), (7), (7), (6), (6), (5), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1)
(95), (31), (31), (2), (1), (1)
(118), (2)
(6), (6), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(80), (48), (46), (33), (24), (21), (16), (11), (9), (6), (4), (1)
Pubmed 2 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 223-254 amino acids from the C-terminal region of human TFAM
Isotype Ig
Specificity This antibody detects TFAM (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A column followed by peptide affinity purification
Alternative Name TFAM / TCF6 (TFAM Antibody Abstract)
Background This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.Synonyms: Mitochondrial transcription factor 1, MtTF1, TCF-6, TCF6L2, Transcription factor 6, Transcription factor 6-like 2, mitochondrial Transcription factor A
Gene ID 7019
NCBI Accession NP_003192
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 223-254), (C-Term) antibody (ABIN955168) TFAM Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compa...
Immunofluorescence (IF) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 223-254), (C-Term) antibody (ABIN955168) Confocal immunofluorescent analysis of TFAM Antibody (C-term) with Hela cell followed...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 223-254), (C-Term) antibody (ABIN955168) TFAM antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Western Blotting (WB) image for anti-Transcription Factor A, Mitochondrial (TFAM) (AA 223-254), (C-Term) antibody (ABIN955168) TFAM Antibody (C-term) western blot analysis in K562 cell line lysates (35 µg/lane). ...
Background publications Corneveaux, Myers, Allen et al.: "Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals." in: Human molecular genetics, Vol. 19, Issue 16, pp. 3295-301, 2010 (PubMed).

Akhmetov, Popov, Missina et al.: "[Association of the mitochondrial transcription factor (TFAM) gene polymorphism with physical performance of athletes]." in: Fiziologiia cheloveka, Vol. 36, Issue 2, pp. 121-5, 2010 (PubMed).

Catalog No. ABIN955168
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