TLE4 antibody (N-Term)

Catalog No. ABIN955232

Product Details anti-TLE4 Antibody

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Binding Specificity: AA 166-196, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE4 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects TLE4 (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 166-196 amino acids from the N-terminal region of human TLE4

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TLE4

Target: TLE4 (Transducin-like Enhancer Protein 4 (TLE4))

Alternative Name: TLE4 (TLE4 Products)

Synonyms: TLE4 antibody, NV17443 antibody, BCE-1 antibody, BCE1 antibody, E(spI) antibody, ESG antibody, ESG4 antibody, GRG4 antibody, Esp2 antibody, Grg4 antibody, XGrg-4 antibody, XTCF-4 antibody, Xgrg4 antibody, Xtle4 antibody, esg4 antibody, grg4 antibody, gro antibody, 5730411M05Rik antibody, AA792082 antibody, Bce-1 antibody, Bce1 antibody, ESTM13 antibody, ESTM14 antibody, X83332 antibody, X83333 antibody, transducin like enhancer of split 4 antibody, transducin-like enhancer protein 4 antibody, protein groucho-1 antibody, transducin-like enhancer of split 4 antibody, transducin like enhancer of split 4-Z 1 antibody, transducin like enhancer of split 4 S homeolog antibody, TLE4 antibody, LOC706619 antibody, LOC100117159 antibody, LOC100462498 antibody, Tle4 antibody, TLE4Z1 antibody, LOC476317 antibody, tle4.S antibody

Background: TLE4 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).Synonyms: GRG4, Groucho-related protein 4, KIAA1261, Transducin-like enhancer protein 4

Gene ID: 7091

NCBI Accession: NP_008936

Pathways: WNT Signaling