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Transmembrane Protein 173 (TMEM173) (C-Term), (AA 318-348) antibody

Details for Product No. ABIN955253
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Antigen
Synonyms ERIS, MITA, MPYS, NET23, STING, 2610307O08Rik, Mita, RGD1562552
Epitope
C-Term, AA 318-348
(24), (15), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(69), (25), (15), (12), (12), (12)
Host
Rabbit
(52), (20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Flow Cytometry (FACS)
(49), (37), (18), (13), (12), (11), (10), (2), (2), (1)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN955253
357.50 $
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Immunogen KLH conjugated synthetic peptide between 318~348 amino acids from the C-terminal region of human TM173
Specificity This antibody detects TMEM173 / STING (C-term).
Purification Protein A column followed by peptide affinity purification
Alternative Name TMEM173 / STING
Background Alternate names: MITA, Mediator of IRF3 activation, Stimulator of interferon genes protein, Transmembrane protein 173
Gene ID 340061
NCBI Accession NP_938023
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Jin, Waterman, Jonscher et al.: "MPYS, a novel membrane tetraspanner, is associated with major histocompatibility complex class II and mediates transduction of apoptotic signals." in: Molecular and cellular biology, Vol. 28, Issue 16, pp. 5014-26, 2008 (PubMed).

Ishikawa, Barber: "STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling." in: Nature, Vol. 455, Issue 7213, pp. 674-8, 2008 (PubMed).

Zhong, Zhang, Lei et al.: "The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA." in: Immunity, Vol. 30, Issue 3, pp. 397-407, 2009 (PubMed).

Sun, Li, Chen et al.: "ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 21, pp. 8653-8, 2009 (PubMed).

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