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Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 216-245), (Middle Region) antibody

Details for Product No. ABIN955275, Supplier: Login to see
Antigen
  • ATAR
  • CD270
  • HVEA
  • HVEM
  • LIGHTR
  • TR2
  • Atar
  • HveA
  • Hvem
  • Tnfrs14
Epitope
AA 216-245, Middle Region
21
18
11
9
9
9
8
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
147
22
1
Host
Rabbit
78
54
16
8
5
Clonality
Polyclonal
Conjugate
Un-conjugated
14
12
7
6
4
3
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
108
62
54
31
20
12
11
8
8
2
1
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 216~245 amino acids from the Center region of human TNFRSF14
Isotype Ig
Specificity This antibody detects TNFRSF14 / HVEM (Center).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A column followed by peptide affinity purification
Alternative Name TNFRSF14 / HVEM (TNFRSF14 Antibody Abstract)
Background TNFRSF14 is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.Synonyms: HVEA, Herpesvirus entry mediator A, TR2, Tumor necrosis factor receptor superfamily member 14, Tumor necrosis factor receptor-like 2
Gene ID 8764
NCBI Accession NP_003811
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 216-245), (Middle Region) antibody (ABIN955275) TNFRSF14 Antibody (Center) flow cytometric analysis of HL-60 cells (bottom histogram)...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 216-245), (Middle Region) antibody (ABIN955275) Formalin-fixed and paraffin-embedded human lung carcinoma reacted with TNFRSF14 Antib...
Western Blotting (WB) image for anti-Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) (AA 216-245), (Middle Region) antibody (ABIN955275) Western blot analysis of anti-TNFRSF14 Antibody (Center) Pab pre-incubated without(la...
Background publications Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

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