TOR2A antibody (Middle Region)

Catalog No. ABIN955296

Product Details anti-TOR2A Antibody

Target: TOR2A (Torsin Family 2, Member A (TOR2A))

Binding Specificity: AA 201-229, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOR2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Torsin-2A (TOR2A) (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 201-229 amino acids from the Central region of human TOR2A

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for TOR2A

Target: TOR2A (Torsin Family 2, Member A (TOR2A))

Alternative Name: Torsin-2A (TOR2A) (TOR2A Products)

Synonyms: tor2a antibody, TOR2A antibody, zgc:114110 antibody, TORP1 antibody, Prosalusin antibody, Torsin-2A antibody, torsin family 2 member A antibody, torsin family 2, member A L homeolog antibody, torsin family 2, member A antibody, TOR2A antibody, tor2a.L antibody, tor2a antibody, Tor2a antibody

Background: Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis, it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.Synonyms: TORP1, Torsin family 2 member A, Torsin-related protein 1

Gene ID: 27433

NCBI Accession: NP_001078816