TRPC4 antibody (Transient Receptor Potential Cation Channel, Subfamily C, Member 4) (C-Term)

Details for Product anti-TRPC4 Antibody No. ABIN955338, Supplier: Log in to see
Antigen
  • TRPC5
  • TRPC4
  • HTRP-4
  • HTRP4
  • TRP4
  • CCE1
  • STRPC4
  • Trp4
  • Trrp4
  • transient receptor potential cation channel, subfamily C, member 4
  • TRPC4
  • trpc4
  • LOC100353818
  • Trpc4
Epitope
C-Term, AA 811-840
40
26
10
8
5
4
2
2
1
1
1
1
Reactivity
Human
90
89
63
4
4
3
2
1
1
1
Host
Rabbit
58
45
19
3
Clonality
Polyclonal
Conjugate
This TRPC4 antibody is un-conjugated
6
5
5
5
5
4
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
120
53
52
49
46
34
25
18
2
2
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen KLH conjugated synthetic peptide between 811-840 amino acids from the C-terminal region of human TRPC4
Isotype Ig
Specificity This antibody detects TRPC4 / TRP4 (C-term).
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Protein A column followed by peptide affinity purification
Alternative Name TRPC4 (TRPC4 Antibody Abstract)
Background Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion.Synonyms: CCE1, Capacitative calcium entry channel 1, Short transient receptor potential channel 4, TRP-4, Trp-related protein 4
Gene ID 7223
NCBI Accession NP_001129427
Research Area Signaling, Tyrosine Kinases
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-TRPC4 antibody (Transient Receptor Potential Cation Channel, Subfamily C, Member 4) (C-Term) (ABIN955338) TRPC4 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35 µg/la...
Background publications Mace, Lussier, Boulay, Terry-Powers, Parfrey, Perraud, Riches: "TRUSS, TNF-R1, and TRPC ion channels synergistically reverse endoplasmic reticulum Ca2+ storage reduction in response to m1 muscarinic acetylcholine receptor signaling." in: Journal of cellular physiology, Vol. 225, Issue 2, pp. 444-53, 2010 (PubMed).

von Spiczak, Muhle, Helbig, de Kovel, Hampe, Gaus, Koeleman, Lindhout, Schreiber, Sander, Stephani: "Association study of TRPC4 as a candidate gene for generalized epilepsy with photosensitivity." in: Neuromolecular medicine, Vol. 12, Issue 3, pp. 292-9, 2010 (PubMed).

Pinheiro, Bulik, Thornton, Sullivan, Root, Bloss, Berrettini, Schork, Kaye, Bergen, Magistretti, Brandt, Crawford, Crow, Fichter, Goldman, Halmi, Johnson, Kaplan, Keel, Klump, La Via, Mitchell, Strober, Rotondo, Treasure, Woodside: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Did you look for something else?