NPRL2 antibody (C-Term)
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- Target See all NPRL2 Antibodies
- NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
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Binding Specificity
- AA 345-373, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NPRL2 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody reacts to NPRL2.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human.
- Purification
- Affinity chromatography on Protein A
- Immunogen
- KLH conjugated synthetic peptide between 345-373 amino acids from the C-terminal region of human NPRL2
- Isotype
- Ig Fraction
- Top Product
- Discover our top product NPRL2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS, 0.09 % (W/V) sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- NPRL2 (Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
- Alternative Name
- TUSC4 / NPRL2 (NPRL2 Products)
- Synonyms
- 2810446G01Rik antibody, G21 antibody, NPR2L antibody, Tusc4 antibody, npr2 antibody, npr2l antibody, tusc4 antibody, NPR2 antibody, TUSC4 antibody, im:6900399 antibody, zgc:153630 antibody, nitrogen permease regulator-like 2 antibody, NPR2 like, GATOR1 complex subunit S homeolog antibody, NPR2 like, GATOR1 complex subunit antibody, NPR2-like, GATOR1 complex subunit antibody, Nprl2 antibody, nprl2.S antibody, NPRL2 antibody, nprl2 antibody
- Background
- Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.Synonyms: Gene 21 protein, NPR2-like, Tumor suppressor candidate 4
- Molecular Weight
- 43658 Da
- Gene ID
- 10641
- NCBI Accession
- NP_006536
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