U2 SnRNP Protein B2 (N-Term), (AA 7-36) antibody

Details for Product No. ABIN955415
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Antigen
Epitope
N-Term, AA 7-36
(1)
Reactivity
Human
(1)
Host
Rabbit
(1)
Clonality
Polyclonal
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(1)
Pubmed 3 references available
Quantity 0.4 mL
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Catalog No. ABIN955415
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Immunogen KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human SNRPB2
Isotype Ig
Specificity This antibody reacts to SNRPB2.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Background The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene.Synonyms: SNRPB2, U2 small nuclear ribonucleoprotein B, U2 snRNP B''
Molecular Weight 25486 Da
Gene ID 6629
NCBI Accession NP_003083
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Chung, Zhou, Huddleston et al.: "Crooked neck is a component of the human spliceosome and implicated in the splicing process." in: Biochimica et biophysica acta, Vol. 1576, Issue 3, pp. 287-97, 2002 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Oh, Yang, Hahn et al.: "Transcriptome analysis of human gastric cancer." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 16, Issue 12, pp. 942-54, 2005 (PubMed).

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