UGT8 antibody (Middle Region)

Catalog No. ABIN955446

Product Details anti-UGT8 Antibody

Target: UGT8 (UDP Glycosyltransferase 8 (UGT8))

Binding Specificity: AA 373-401, Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects UGT8 / UGT4 (Center).

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 373-401 amino acids from the Central region of human UGT8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for UGT8

Target: UGT8 (UDP Glycosyltransferase 8 (UGT8))

Alternative Name: UGT8 / UGT4 (UGT8 Products)

Synonyms: Xlcgt antibody, cgt antibody, ugt4 antibody, AI850488 antibody, AW455908 antibody, Cgt antibody, Ugt8 antibody, mCerGT antibody, CGT antibody, UGT4 antibody, Ugt8a antibody, UDP glycosyltransferase 8 antibody, UDP galactosyltransferase 8A antibody, UGT8 antibody, ugt8 antibody, Ugt8a antibody, Ugt8 antibody

Background: Galactocerebrosides are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system and are also present in small amounts in kidney. The key enzymatic step in the biosynthesis of galactocerebrosides consists of the transfer of galactose to ceramide catalyzed by UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45). The enzyme encoded by the CGT gene is the first involved in complex lipid biosynthesis in the myelinating oligodendrocyte.[supplied by OMIM].Synonyms: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase, CGT, Ceramide UDP-galactosyltransferase, Cerebroside synthase, UDP-galactose-ceramide galactosyltransferase

Gene ID: 7368

NCBI Accession: NP_001121646

Pathways: Cell-Cell Junction Organization