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USF1 antibody (Upstream Transcription Factor 1) (AA 174-201)

Details for Product anti-USF1 Antibody No. ABIN955484, Supplier: Log in to see
Antigen
  • bhlhb11
  • bHLHb11
  • DKFZp469G215
  • FCHL
  • fchl
  • fchl1
  • FCHL1
  • HYPLIP1
  • hyplip1
  • MLTF
  • mltf
  • mltfi
  • MLTFI
  • rUSF1a
  • uef
  • UEF
  • usf1
  • USF1
  • zgc:56547
Epitope
AA 174-201, Middle Region
12
9
7
5
3
2
2
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
50
17
11
3
3
3
3
2
2
Host
Rabbit
38
12
Clonality
Polyclonal
Conjugate
This USF1 antibody is un-conjugated
3
3
3
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
43
22
19
14
7
2
2
2
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 174-201 amino acids from the Central region of human USF1
Isotype Ig
Specificity This antibody detects USF1 (Center).
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Protein A column followed by peptide affinity purification
Alternative Name USF1 (USF1 Antibody Abstract)
Background This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Two transcript variants encoding distinct isoforms have been identified for this gene.Synonyms: Major late transcription factor 1, USF, Upstream stimulatory factor 1
Gene ID 7391
NCBI Accession NP_009053
Research Area Cancer, Atherosclerosis, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-USF1 antibody (Upstream Transcription Factor 1) (AA 174-201) (ABIN955484) USF1 Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram) comp...
Immunofluorescence (IF) image for anti-USF1 antibody (Upstream Transcription Factor 1) (AA 174-201) (ABIN955484) Confocal immunofluorescent analysis of USF1 Antibody (Center) with Hela cell followed...
Western Blotting (WB) image for anti-USF1 antibody (Upstream Transcription Factor 1) (AA 174-201) (ABIN955484) USF1 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35 µg/la...
Background publications Bussière, Michel, Mémet, Avé, Vivas, Huerre, Touati: "H. pylori-induced promoter hypermethylation downregulates USF1 and USF2 transcription factor gene expression." in: Cellular microbiology, Vol. 12, Issue 8, pp. 1124-33, 2010 (PubMed).

Singmann, Baumert, Herder, Meisinger, Holzapfel, Klopp, Wichmann, Klingenspor, Rathmann, Illig, Grallert: "Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome." in: Obesity facts, Vol. 2, Issue 4, pp. 235-42, 2010 (PubMed).

Jablonski, McAteer, de Bakker, Franks, Pollin, Hanson, Saxena, Fowler, Shuldiner, Knowler, Altshuler, Florez: "Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program." in: Diabetes, Vol. 59, Issue 10, pp. 2672-81, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Naukkarinen, Nilsson, Koistinen, Söderlund, Lyssenko, Vaag, Poulsen, Groop, Taskinen, Peltonen: "Functional variant disrupts insulin induction of USF1: mechanism for USF1-associated dyslipidemias." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 5, pp. 522-9, 2009 (PubMed).