WIPI2 antibody (C-Term)

Catalog No. ABIN955579

Product Details anti-WIPI2 Antibody

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Binding Specificity: AA 422-451, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIPI2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects WIPI-2 (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 422~451 amino acids from the C-terminal region of human WIPI2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for WIPI2

Target: WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

Alternative Name: WIPI-2 (WIPI2 Products)

Synonyms: ATG18B antibody, Atg21 antibody, WIPI-2 antibody, 1110018O08Rik antibody, 2510001I10Rik antibody, WD repeat domain, phosphoinositide interacting 2 L homeolog antibody, WD repeat domain, phosphoinositide interacting 2 antibody, wipi2.L antibody, WIPI2 antibody, Wipi2 antibody

Background: WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).Synonyms: CGI-50, WD repeat domain phosphoinositide-interacting protein 2, WIPI2, WIPI49-like protein 2

Gene ID: 26100

NCBI Accession: NP_001028690