XCR1 antibody (C-Term)

Catalog No. ABIN955596

Product Details anti-XCR1 Antibody

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Binding Specificity: AA 302-333, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XCR1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects XCR1 / GPR5 (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 302-333 amino acids from the C-terminal region of human XCR1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for XCR1

Target: XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))

Alternative Name: XCR1 / GPR5 (XCR1 Products)

Synonyms: CCXCR1-L antibody, XCR1 antibody, CCXCR1 antibody, GPR5 antibody, Ccxcr1 antibody, Gpr5 antibody, mXcr1 antibody, X-C motif chemokine receptor 1 antibody, chemokine (C motif) receptor 1a, duplicate 1 antibody, chemokine (C motif) receptor 1 antibody, XCR1 antibody, xcr1a.1 antibody, Xcr1 antibody

Background: The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.Synonyms: CCXCR1, Chemokine XC receptor 1, G-protein coupled receptor 5, Lymphotactin receptor, XC chemokine receptor 1

Gene ID: 2829

NCBI Accession: NP_001019815