ZC3H8 antibody (N-Term)

Catalog No. ABIN955638

Product Details anti-ZC3H8 Antibody

Target: ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))

Binding Specificity: AA 59-90, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC3H8 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ZC3H8 (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 59-90 amino acids from the N-terminal region of human ZC3H8

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for ZC3H8

Target: ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))

Alternative Name: ZC3H8 (ZC3H8 Products)

Synonyms: Zc3hdc8 antibody, DKFZp459D018 antibody, AU020882 antibody, E130108N08Rik antibody, Fliz1 antibody, ZC3HDC8 antibody, zinc finger CCCH type containing 8 antibody, zinc finger CCCH-type containing 8 antibody, Zc3h8 antibody, ZC3H8 antibody

Background: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.Synonyms: Fliz1, ZC3HDC8, Zinc finger CCCH domain-containing protein 8

Gene ID: 84524

NCBI Accession: NP_115883