PCSK1 antibody (AA 683-732)

Catalog No. ABIN6748492

Product Details anti-PCSK1 Antibody

Target: PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))

Binding Specificity: AA 683-732

Reactivity: Human, Guinea Pig, Horse, Cow, Dog, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCSK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human PCSK1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Dog, Bovine, Horse (100%) Rabbit, Pig (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa683-732 of human PCSK1 (P29120, NP_000430). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Panda, Dog, Bovine, Horse, Guinea pig (100%), Rat, Rabbit, Pig, Chicken (92%), Galago, Elephant, Bat (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for PCSK1

Target: PCSK1 (Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1))

Alternative Name: PCSK1 / PC1 (PCSK1 Products)

Synonyms: BMIQ12 antibody, NEC1 antibody, PC1 antibody, PC3 antibody, SPC3 antibody, Nec-1 antibody, Nec1 antibody, Phpp-1 antibody, BDP antibody, PC1/3 antibody, proprotein convertase subtilisin/kexin type 1 antibody, prohormone convertase 1 antibody, PCSK1 antibody, Pcsk1 antibody, pcsk1 antibody, PC1B antibody

Background: Name/Gene ID: PCSK1
Subfamily: Serine S8
Family: Protease

Synonyms: PCSK1, Pc1/3, PC1, Prohormone convertase 3, SPC3, Neuroendocrine convertase 1, PC3, Prohormone convertase 1, BMIQ12, NEC 1, NEC1, Proprotein convertase 1

Gene ID: 5122

NCBI Accession: NP_000430

UniProt: P29120

Pathways: Peptide Hormone Metabolism