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Cathepsin D (CTSD) antibody

Antigen

Cathepsin D (CTSD)

Synonyms CPSD, CLN10, MGC2311, CD, CatD, catD, fb93e11, fj17b09, wu:fb93e11, wu:fj17b09, CTSD, LOC398557, Cathd, LOC100136761, DKFZp469J0315
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Application
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
1 reference available
Catalog no. ABIN96161
Quantity 6ml  (1 to 4 ug/ml)  (Variants)
Price 82.00 $   Plus shipping costs $35.00
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Additional Information

Alternative name Cathepsin D
Immunogen Cathepsin D isolated from human liver.
Format Ig-fraction, Liquid (prediluted)
Specificity This antibody reacts with the zymogen as well as the activated form of cathepsin D. It stains fibroblasts and macrophages strongly but stains weakly with the myoepithelial cells of breast. It stains the sweat ducts and glands in the skin, islets cells and granules of pancreatic acini.

Application Details

Application Notes Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions should be determined by the user. Suitable for formalin/paraffin tissues. Positive Control: Breast carcinoma. Cellular localization: Cytoplasmic
Concentration 1 to 4 ug/ml
Buffer This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required.
Storage Store the antibody at 2-8o c. Do not use it beyond the expiration date stated on the label.
Research Area Proteases
Restrictions For Research Use. CE-certified for In Vitro Diagnostics (IVD) Use in the European Union

Publications

Publications Henry, McCarthy, Angus et al.: "Prognostic significance of the estrogen-regulated protein, cathepsin D, in breast cancer. An immunohistochemical study." in: Cancer, Vol. 65, Issue 2, pp. 265-71, 1990 (PubMed).