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Smooth Muscle Actin antibody (Actin, alpha 2, Smooth Muscle, Aorta)

Details for Product anti-ACTA2 Antibody No. ABIN965505, Supplier: Log in to see
Antigen
  • 0610041G09Rik
  • a-sma
  • a-SMA
  • aat6
  • AAT6
  • ACT-4
  • ACTA2
  • actc1
  • ACTSA
  • actsa
  • Actvs
  • alphaSMA
  • ASMA
  • asma
  • MYMY5
  • mymy5
  • sm-actin
  • SMactin
  • SMalphaA
  • wu:fb63d03
Reactivity
Human, Monkey, Rat (Rattus), Mouse (Murine)
205
77
72
26
22
18
15
13
8
6
5
5
4
3
3
2
2
1
1
Host
Mouse
110
85
15
Clonality (Clone)
Monoclonal ()
Conjugate
This Smooth Muscle Actin antibody is un-conjugated
8
4
3
3
3
3
2
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Western Blotting (WB)
127
108
67
58
40
34
16
14
6
3
1
1
Supplier
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Immunogen Purified recombinant fragment of human ACTA2 expressed in E. Coli.
Clone 1H8
Purification Ascitic fluid
Alternative Name ACTA2 (ACTA2 Antibody Abstract)
Background Actin,alpha 2, smooth muscle, aorta, major constituent of thin filaments.
Gene ID 59
Application Notes Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Background publications Guo, Pannu, Tran-Fadulu, Papke, Yu, Avidan, Bourgeois, Estrera, Safi, Sparks, Amor, Ades, McConnell, Willoughby, Abuelo, Willing, Lewis, Kim, Scherer, Tung, Ahn, Buja, Raman, Shete, Milewicz: "Mutations in smooth muscle alpha-actin (ACTA2) lead to thoracic aortic aneurysms and dissections." in: Nature genetics, Vol. 39, Issue 12, pp. 1488-93, 2007 (PubMed).

Product cited in: Salas, Bartoli, Deville, Gaudart, Fina, Calisti, Bollini, Curvale, Gentet, Duffaud, Figarella-Branger, Bouvier: "Ezrin and alpha-smooth muscle actin are immunohistochemical prognostic markers in conventional osteosarcomas." in: Virchows Archiv : an international journal of pathology, Vol. 451, Issue 6, pp. 999-1007, 2007 (PubMed).