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FOXO4 antibody (Forkhead Box O4) (pSer197)

Details for Product anti-FOXO4 Antibody No. ABIN965516, Supplier: Login to see New
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Antigen
Synonyms FOXO4, foxo4, AFX, AFX1, MLLT7, Afxh, Mllt7, afx, RGD1561201
Alternatives
Epitope
pSer197
(37), (37), (23), (20), (17), (11), (9), (7), (5), (5), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(248), (138), (98), (7), (5), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(226), (16), (7)
Conjugate
This FOXO4 antibody is un-conjugated
(6), (6), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(188), (90), (76), (35), (35), (34), (22), (7), (5), (1), (1)
Pubmed 3 references available
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Quantity 100 μg
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human AFX around the phosphorylation site of serine 197 (A-A-SP-M-D).
Specificity AFX (phospho-Ser197) antibody detects endogenous levels of AFX only when phosphorylated at serine 197. .
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name AFX (FOXO4 Antibody Abstract)
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Di, Hao, Gao et al.: "Monoclonal antibody-based antigen capture enzyme-linked immunosorbent assay reveals high sensitivity of the nucleocapsid protein in acute-phase sera of severe acute respiratory syndrome patients." in: Clinical and diagnostic laboratory immunology, Vol. 12, Issue 1, pp. 135-40, 2005 (PubMed).

Kops, de Ruiter, De Vries-Smits et al.: "Direct control of the Forkhead transcription factor AFX by protein kinase B." in: Nature, Vol. 398, Issue 6728, pp. 630-4, 1999 (PubMed).

Background publications Brownawell, Kops, Macara et al.: "Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX." in: Molecular and cellular biology, Vol. 21, Issue 10, pp. 3534-46, 2001 (PubMed).

Catalog No. ABIN965516
$398.75
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