anti-AKT antibody (V-Akt Murine Thymoma Viral Oncogene Homolog 1) (pSer473)

Details for Product anti-AKT1 Antibody No. ABIN965523, Supplier: Login to see New
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Antigen
Synonyms
AKT, AKT1, pkb, xAct, v-akt, v-akt1, akt-1, AKT/PKB, Akt, Akt/PKB, Akt1, PKB, CG4006, D-Akt, DAKT1, DAKT1/PKB, DAkt, DAkt1, DPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, Dakt, Dakt1, Dmel\\CG4006, Dpkb, PKB/AK ... show more
AKT, AKT1, pkb, xAct, v-akt, v-akt1, akt-1, AKT/PKB, Akt, Akt/PKB, Akt1, PKB, CG4006, D-Akt, DAKT1, DAKT1/PKB, DAkt, DAkt1, DPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, Dakt, Dakt1, Dmel\\CG4006, Dpkb, PKB/AKT, PKB/Akt, PKB/dAKT, RAC, RacPK, akt, akt1, dAKT, dAKT/dPKB, dAKT1, dAkt, dAkt/PKB, dAkt1, dPKB, dakt, dakt1, l(3)04226, l(3)89Bq, p-Akt, pAkt, ATAKT1, F18A8.2, F18A8_2, K+ transporter 1, POTASSIUM TRANSPORTER, Rac, PKBalpha, CWS6, PKB-ALPHA, PRKBA, RAC-ALPHA show less
Alternatives
Epitope
pSer473
(154), (119), (97), (90), (62), (50), (41), (41), (25), (24), (21), (20), (19), (16), (15), (15), (14), (13), (12), (11), (11), (10), (8), (7), (7), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(1171), (555), (454), (46), (39), (31), (30), (18), (15), (11), (10), (6), (5), (4), (3), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(976), (215), (15), (6), (1)
Conjugate
This AKT antibody is un-conjugated
(38), (32), (32), (30), (28), (24), (10), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(971), (569), (461), (222), (135), (112), (107), (65), (56), (36), (33), (13), (9), (7), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Quantity 100 μg
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Akt around the phosphorylation site of serine 473 (Q-F-SP-Y-S).
Specificity Akt (phospho-Ser473) antibody detects endogenous levels of Akt only when phosphorylated at serine 473.
Alternative Name Akt (AKT1 Antibody Abstract)
Pathways PI3K-Akt Signaling, RTK Signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Feng, Tamaskovic, Yang et al.: "Stabilization of Mdm2 via decreased ubiquitination is mediated by protein kinase B/Akt-dependent phosphorylation." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 35510-7, 2004 (PubMed).

Background publications Min, Cheong, Kim et al.: "Cytoplasmic mislocalization of p27Kip1 protein is associated with constitutive phosphorylation of Akt or protein kinase B and poor prognosis in acute myelogenous leukemia." in: Cancer research, Vol. 64, Issue 15, pp. 5225-31, 2004 (PubMed).

Baudhuin, Jiang, Zaslavsky et al.: "S1P3-mediated Akt activation and cross-talk with platelet-derived growth factor receptor (PDGFR)." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 18, Issue 2, pp. 341-3, 2004 (PubMed).

Catalog No. ABIN965523
$398.75
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