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AKT antibody (V-Akt Murine Thymoma Viral Oncogene Homolog 1) (pThr308)

Details for Product anti-AKT1 Antibody No. ABIN965524, Supplier: Log in to see
Antigen
  • Akt
  • akt
  • AKT
  • akt-1
  • Akt/PKB
  • AKT/PKB
  • AKT1
  • akt1
  • Akt1
  • ATAKT1
  • CG4006
  • CWS6
  • D-Akt
  • dAKT
  • dakt
  • dAkt
  • Dakt
  • DAkt
  • dAKT/dPKB
  • dAkt/PKB
  • dakt1
  • dAkt1
  • dAKT1
  • DAkt1
  • DAKT1
  • Dakt1
  • DAKT1/PKB
  • Dmel\\CG4006
  • Dpkb
  • DPKB
  • dPKB
  • DRAC-PK
  • DRAC-PK66
  • DRAC-PK85
  • F18A8.2
  • F18A8_2
  • K+ transporter 1
  • l(3)04226
  • l(3)89Bq
  • p-Akt
  • pAkt
  • pkb
  • PKB
  • PKB-ALPHA
  • PKB/Akt
  • PKB/AKT
  • PKB/dAKT
  • PKBalpha
  • POTASSIUM TRANSPORTER
  • PRKBA
  • Rac
  • RAC
  • RAC-ALPHA
  • RacPK
  • v-akt
  • v-akt1
  • xAct
Alternatives
anti-Human AKT antibody for Western Blotting
Epitope
pThr308
188
136
89
87
54
38
38
37
26
25
21
21
21
19
16
15
15
15
14
13
11
11
10
8
7
6
6
5
5
5
5
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1162
542
410
44
41
37
34
32
20
18
11
6
5
4
2
2
2
1
1
Host
Rabbit
893
312
14
4
1
Conjugate
This AKT antibody is un-conjugated
45
39
35
34
26
25
10
10
5
5
5
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
975
554
445
223
143
120
117
71
63
36
25
11
11
5
3
3
3
3
2
1
1
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Akt around the phosphorylation site of threonine 308 (M-K-TP-F-C).
Specificity Akt (phospho-Thr308) antibody detects endogenous levels of Akt only when phosphorylated at threonine 308.
Alternative Name Akt (AKT1 Antibody Abstract)
Pathways PI3K-Akt Signaling, RTK Signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Tremblay, Krebs, Dombrowski, Brehm, Bernroider, Roth, Nowotny, Waldhäusl, Marette, Roden: "Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability." in: Diabetes, Vol. 54, Issue 9, pp. 2674-84, 2005 (PubMed).

Xu, Stippec, Lazrak, Huang, Cobb: "WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism." in: The Journal of biological chemistry, Vol. 280, Issue 40, pp. 34218-23, 2005 (PubMed).

Product cited in: Samuels, Diaz, Schmidt-Kittler, Cummins, Delong, Cheong, Rago, Huso, Lengauer, Kinzler, Vogelstein, Velculescu: "Mutant PIK3CA promotes cell growth and invasion of human cancer cells." in: Cancer cell, Vol. 7, Issue 6, pp. 561-73, 2005 (PubMed).

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