APOBEC3G antibody (N-Term)

Catalog No. ABIN965574

Product Details anti-APOBEC3G Antibody

Target: APOBEC3G (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOBEC3G antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human APOBEC3G (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-APOBEC3G antibody (ABIN965574)

Pido-Lopez, Jeffrey, Wang, Seidl, Babaahmady, Vaughan, Lehner: "The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4(+) T-cell APOBEC3G expression and HIV-1 infectivity." in: European journal of immunology, Vol. 39, Issue 7, pp. 1956-65, (2009) (PubMed).

Chen, He, Wang, Xu, Yu: "A patch of positively charged amino acids surrounding the human immunodeficiency virus type 1 Vif SLVx4Yx9Y motif influences its interaction with APOBEC3G." in: Journal of virology, Vol. 83, Issue 17, pp. 8674-82, (2009) (PubMed).

Dang, Wang, Zhou, York, Zheng: "Identification of a novel WxSLVK motif in the N terminus of human immunodeficiency virus and simian immunodeficiency virus Vif that is critical for APOBEC3G and APOBEC3F neutralization." in: Journal of virology, Vol. 83, Issue 17, pp. 8544-52, (2009) (PubMed).

Vetter, DAquila: "Cytoplasmic APOBEC3G restricts incoming Vif-positive human immunodeficiency virus type 1 and increases two-long terminal repeat circle formation in activated T-helper-subtype cells." in: Journal of virology, Vol. 83, Issue 17, pp. 8646-54, (2009) (PubMed).

Kamada, Igarashi, Martin, Khamsri, Hatcho, Yamashita, Fujita, Uchiyama, Adachi: "Generation of HIV-1 derivatives that productively infect macaque monkey lymphoid cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 45, pp. 16959-64, (2006) (PubMed).

Target Details for APOBEC3G

Target: APOBEC3G (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G))

Alternative Name: APOBEC3G (APOBEC3G Products)

Synonyms: A3G antibody, ARCD antibody, ARP-9 antibody, ARP9 antibody, CEM-15 antibody, CEM15 antibody, bK150C2.7 antibody, dJ494G10.1 antibody, apolipoprotein B mRNA editing enzyme catalytic subunit 3G antibody, APOBEC3G antibody

Background: APOBEC3G (apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3G) is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. APOBEC3G is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. APOBEC3G has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.