anti-ATF2 antibody (Activating Transcription Factor 2) (pThr51)

Details for Product anti-ATF2 Antibody No. ABIN965607
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Antigen
Synonyms CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420, CRE-BP1, CREB2, HB16, TREB7, Atf-2, CRE-BP, Creb2, D130078H02Rik, D18875, Tg(Gzma-Klra1)7Wum, mXBP, atf2-A, atf2l, ATF1, ATF2, HFB1-GDNF, HSCR3
Epitope
pThr51, pThr69
(49), (45), (40), (35), (33), (32), (31), (29), (28), (27), (26), (26), (20), (20), (14), (12), (12), (10), (10), (8), (8), (8), (8), (7), (7), (7), (7), (6), (6), (6), (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(595), (330), (317), (7), (5), (3), (2), (2), (1), (1), (1), (1), (1)
Host
Rabbit
(544), (28), (19), (7)
Conjugate
This ATF2 antibody is un-conjugated
(16), (16), (16), (10), (10), (10), (10), (10), (10), (10), (10), (6), (6), (6)
Application
Immunohistochemistry (IHC)
(412), (271), (173), (100), (97), (97), (95), (20), (10), (9), (9), (5), (3), (2), (2), (1), (1), (1), (1)
Pubmed 4 references available
Quantity 100 μg
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 69 or 51 (D-Q-TP-P-T).
Specificity ATF-2 (hosphor-Thr69 or 51) antibody detects endogenous levels of ATF-2 only when phosphorylated at threonine 69 or 51.
Alternative Name ATF2 (ATF2 Antibody Abstract)
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways MAPK Pathway
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Alsayed, Uddin, Mahmud et al.: "Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid." in: The Journal of biological chemistry, Vol. 276, Issue 6, pp. 4012-9, 2001 (PubMed).

Background publications Sevilla, Santos, Vega et al.: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, 2004 (PubMed).

Gupta, Campbell, Dérijard et al.: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, 1995 (PubMed).

Abdel-Hafiz, Heasley, Kyriakis et al.: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, 1993 (PubMed).

Validation Images
Catalog No. ABIN965607
398.75 $
Plus shipping costs $45.00
Quantity
Price
100 μg
398.75 $

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