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ATF2 antibody (Activating Transcription Factor 2) (pThr51)

Details for Product anti-ATF2 Antibody No. ABIN965607, Supplier: Log in to see
Antigen
  • Atf-2
  • ATF1
  • ATF2
  • atf2-A
  • atf2l
  • CG3749
  • CG12850
  • CG30420
  • CHN1
  • CRE-BP
  • CRE-BP1
  • Creb2
  • CREB2
  • D18875
  • D130078H02Rik
  • dATF-2
  • DmelCG30420
  • HB16
  • HFB1-GDNF
  • HSCR3
  • mXBP
  • Tg(Gzma-Klra1)7Wum
  • TREB7
Alternatives
anti-Human ATF2 antibody for Western Blotting
Epitope
pThr51, pThr69
73
46
41
34
33
32
32
32
28
26
26
25
18
18
13
13
13
12
10
10
9
8
8
7
7
7
6
6
6
5
5
5
5
5
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
604
335
307
20
9
6
5
4
2
2
2
1
1
1
1
Host
Rabbit
537
51
15
4
Conjugate
This ATF2 antibody is un-conjugated
16
15
15
10
10
9
9
9
9
9
9
9
7
6
6
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
416
259
156
100
97
94
86
22
21
12
10
8
3
2
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 69 or 51 (D-Q-TP-P-T).
Specificity ATF-2 (hosphor-Thr69 or 51) antibody detects endogenous levels of ATF-2 only when phosphorylated at threonine 69 or 51.
Alternative Name ATF2 (ATF2 Antibody Abstract)
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways MAPK Signaling, RTK Signaling, TCR Signaling
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Sevilla, Santos, Vega, Lazo: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, 2004 (PubMed).

Gupta, Campbell, Dérijard, Davis: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, 1995 (PubMed).

Abdel-Hafiz, Heasley, Kyriakis, Avruch, Kroll, Johnson, Hoeffler: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, 1993 (PubMed).

Product cited in: Alsayed, Uddin, Mahmud, Lekmine, Kalvakolanu, Minucci, Bokoch, Platanias: "Activation of Rac1 and the p38 mitogen-activated protein kinase pathway in response to all-trans-retinoic acid." in: The Journal of biological chemistry, Vol. 276, Issue 6, pp. 4012-9, 2001 (PubMed).