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ATF2 antibody (Activating Transcription Factor 2) (pThr53)

Details for Product anti-ATF2 Antibody No. ABIN965608, Supplier: Log in to see
Antigen
  • CHN1
  • CG12850
  • CG3749
  • dATF-2
  • DmelCG30420
  • CG30420
  • CRE-BP1
  • CREB2
  • HB16
  • TREB7
  • Atf-2
  • CRE-BP
  • Creb2
  • D130078H02Rik
  • D18875
  • Tg(Gzma-Klra1)7Wum
  • mXBP
  • atf2-A
  • atf2l
  • ATF1
  • ATF2
  • HFB1-GDNF
  • HSCR3
Alternatives
anti-Human ATF2 antibody for Western Blotting
Epitope
pThr53, pThr71
53
46
40
34
34
32
31
31
25
25
25
23
18
15
13
13
12
12
10
9
9
9
8
7
7
7
6
6
6
5
5
5
5
5
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
568
324
295
17
10
5
5
4
2
2
1
1
1
1
1
Host
Rabbit
520
32
15
4
Conjugate
This ATF2 antibody is un-conjugated
15
15
15
14
9
9
9
9
9
9
9
9
6
6
6
Application
Immunohistochemistry (IHC)
377
242
152
105
85
82
81
22
10
8
7
3
1
1
1
1
1
1
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 71 or 53 (T-P-TP-P-T).
Specificity ATF-2 (phospho-Thr71 or 53) antibody detects endogenous levels of ATF-2 only when phosphorylated at threonine 71 or 53.
Alternative Name ATF2 (ATF2 Antibody Abstract)
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways MAPK Signaling, RTK Signaling, TCR Signaling
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Waetzig, Seegert, Rosenstiel et al.: "p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 10, pp. 5342-51, 2002 (PubMed).

van Dam, Wilhelm, Herr et al.: "ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents." in: The EMBO journal, Vol. 14, Issue 8, pp. 1798-811, 1995 (PubMed).

Background publications Sevilla, Santos, Vega et al.: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, 2004 (PubMed).

Gupta, Campbell, Dérijard et al.: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, 1995 (PubMed).

Abdel-Hafiz, Heasley, Kyriakis et al.: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, 1993 (PubMed).