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Details for Product No. ABIN965608

Activating Transcription Factor 2 (ATF2) (pThr53), (pThr71) antibody

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Antigen
Synonyms CRE-BP1, CREB2, HB16, TREB7, Atf-2, CRE-BP, Creb2, D130078H02Rik, D18875, Tg(Gzma-Klra1)7Wum, mXBP, atf2-A, atf2l, CHN1, CG12850, CG3749, dATF-2, DmelCG30420, CG30420
Epitope
»Alternatives pThr53, pThr71
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 5 references available
Catalog no. ABIN965608
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 71 or 53 (T-P-TP-P-T).
Specificity ATF-2 (phospho-Thr71 or 53) antibody detects endogenous levels of ATF-2 only when phosphorylated at threonine 71 or 53.
Alternative Name ATF2
Research Area Immunology, Innate Immunity, Transcription Factors
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Abdel-Hafiz, Heasley, Kyriakis et al.: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, 1993 (PubMed).

van Dam, Wilhelm, Herr et al.: "ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents." in: The EMBO journal, Vol. 14, Issue 8, pp. 1798-811, 1995 (PubMed).

Gupta, Campbell, Dérijard et al.: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, 1995 (PubMed).

Waetzig, Seegert, Rosenstiel et al.: "p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 10, pp. 5342-51, 2002 (PubMed).

Sevilla, Santos, Vega et al.: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, 2004 (PubMed).

Alternatives for antigen "Activating Transcription Factor 2 (ATF2)", type "Antibodies"
Hosts (472), (25), (9), (9)
Reactivities (508), (347), (329), (111), (89), (72), (62), (12), (2), (1), (1), (1), (1), (1)
Applications (291), (161), (160), (152), (132), (86), (50), (13), (11), (11), (3), (3), (2), (1), (1), (1), (1), (1)
Conjugates (16), (16), (16), (16), (16), (16), (16), (16), (16), (16), (16)
Epitopes (63), (59), (50), (44), (31), (29), (28), (28), (21), (20), (20), (18), (17), (17), (17), (16), (11), (9), (7), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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