ATF2 antibody (Activating Transcription Factor 2)

Details for Product anti-ATF2 Antibody No. ABIN965614, Supplier: Log in to see
Antigen
  • CHN1
  • CG12850
  • CG3749
  • dATF-2
  • DmelCG30420
  • CG30420
  • CRE-BP1
  • CREB2
  • HB16
  • TREB7
  • Atf-2
  • CRE-BP
  • Creb2
  • D130078H02Rik
  • D18875
  • Tg(Gzma-Klra1)7Wum
  • mXBP
  • atf2-A
  • atf2l
  • ATF1
  • ATF2
  • HFB1-GDNF
  • HSCR3
  • activating transcription factor 2
  • Activating transcription factor-2
  • glial cell derived neurotrophic factor
  • ATF2
  • Atf-2
  • Atf2
  • atf2
  • LOC100355367
  • GDNF
Alternatives
anti-Human ATF2 antibody for Immunofluorescence (fixed cells)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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4
Clonality
Polyclonal
Conjugate
This ATF2 antibody is un-conjugated
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Application
Immunohistochemistry (IHC)
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2
1
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Options
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Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from human ATF-2 around the phosphorylation site of serine 112 or 94 (D-L-S-PP-L).
Specificity ATF-2 (Ab-112 or 94) antibody detects endogenous levels of total ATF-2 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name ATF2 (ATF2 Antibody Abstract)
Pathways MAPK Signaling, RTK Signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Product cited in: Gupta, Campbell, Dérijard, Davis: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, 1995 (PubMed).

Livingstone, Patel, Jones: "ATF-2 contains a phosphorylation-dependent transcriptional activation domain." in: The EMBO journal, Vol. 14, Issue 8, pp. 1785-97, 1995 (PubMed).

van Dam, Wilhelm, Herr, Steffen, Herrlich, Angel: "ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents." in: The EMBO journal, Vol. 14, Issue 8, pp. 1798-811, 1995 (PubMed).

Abdel-Hafiz, Heasley, Kyriakis, Avruch, Kroll, Johnson, Hoeffler: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, 1993 (PubMed).