Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody

Details for Product No. ABIN965619
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Antigen
Synonyms ATM, Atm, CG6535, Dmel\\CG6535, Tefu, atm, atm/tefu, dATM, tef, Xatm, at1, atdc, tel1, telo1, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1, AI256621, C030026E19Rik
Epitope
pSer1981
(52), (19), (12), (12), (9), (8), (5), (5), (5), (5), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(226), (64), (38), (3), (2), (1), (1)
Host
Rabbit
(162), (41), (16), (7), (3)
Conjugate
Un-conjugated
(7), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1)
Application
Immunohistochemistry (IHC)
(125), (49), (49), (48), (43), (40), (34), (12), (12), (5), (2), (2)
Pubmed 4 references available
Quantity 100 µg
Options
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Catalog No. ABIN965619
385.00 $
Plus shipping costs $45.00

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  • +1 404 474 4654
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human ATM around the phosphorylation site of serine 1981 (E-G-SP-Q-S).
Specificity ATM (phospho-Ser1981) antibody detects endogenous levels of ATM only when phosphorylated at serine 1981.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name ATM
Research Area Cancer, DNA/RNA
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Bernstein, Seminara, Børresen-Dale: "Workshop on The Epidemiology of the ATM Gene: Impact on Breast Cancer Risk and Treatment, Present Status and Future Focus, Lillehammer, Norway, 29 June 2002." in: Breast cancer research : BCR, Vol. 4, Issue 6, pp. 249-52, 2002 (PubMed).

Nakada, Shimomura, Matsumoto et al.: "The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment." in: Nucleic acids research, Vol. 31, Issue 6, pp. 1715-24, 2003 (PubMed).

Silverman, Takai, Buonomo et al.: "Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint." in: Genes & development, Vol. 18, Issue 17, pp. 2108-19, 2004 (PubMed).

Gupta, Sharma, Young et al.: "Involvement of human MOF in ATM function." in: Molecular and cellular biology, Vol. 25, Issue 12, pp. 5292-305, 2005 (PubMed).

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