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AXL Receptor tyrosine Kinase (AXL) (C-Term), (pTyr698), (pTyr702), (pTyr703) antibody

Details for Product No. ABIN965632
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Antigen
Synonyms JTK11, UFO, AI323647, Ark, Tyro7, Ufo
Epitope
C-Term, pTyr698, pTyr702, pTyr703
(17), (17), (17), (15), (13), (7), (6), (6), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(124), (53), (45), (34), (19), (17), (1)
Host
Rabbit
(98), (32), (2), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(99), (62), (42), (28), (28), (16), (12), (7), (5), (4), (2), (1)
Pubmed 7 references available
Quantity 0.1 mg
Options
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Availability Will be delivered in 5 to 7 Business Days
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Catalog No. ABIN965632
452.38 $
Plus shipping costs $45.00

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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human AXL(Tyrosine-protein kinase receptor UFO)
Alternative Name AXL
Background AXL(Tyrosine-protein kinase receptor UFO) may function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, AXL seems to function as a cell entry factor. AXL is heterodimer and heterotetramer with GAS6. AXL is a single-pass type I membrane protein. It is highly expressed in metastatic colon tumors. And weakly expressed in normal colon tissue. AXL belongs to the protein kinase superfamily and Tyr protein kinase family and AXL/UFO subfamily. AXL contains 1 protein kinase domain.
Restrictions For Research Use only
Product cited in: OBryan, Frye, Cogswell et al.: "axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase." in: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5016-31, 1991 (PubMed).

Janssen, Schulz, Steenvoorden et al.: "A novel putative tyrosine kinase receptor with oncogenic potential." in: Oncogene, Vol. 6, Issue 11, pp. 2113-20, 1991 (PubMed).

Partanen, Mäkelä, Alitalo et al.: "Putative tyrosine kinases expressed in K-562 human leukemia cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 22, pp. 8913-7, 1991 (PubMed).

Craven, Xu, Weiner et al.: "Receptor tyrosine kinases expressed in metastatic colon cancer." in: International journal of cancer. Journal international du cancer, Vol. 60, Issue 6, pp. 791-7, 1995 (PubMed).

Lee, Strunk, Spritz: "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes." in: Oncogene, Vol. 8, Issue 12, pp. 3403-10, 1993 (PubMed).

Shimojima, Takada, Ebihara et al.: "Tyro3 family-mediated cell entry of Ebola and Marburg viruses." in: Journal of virology, Vol. 80, Issue 20, pp. 10109-16, 2006 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

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