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AXL antibody (AXL Receptor tyrosine Kinase) (C-Term)

Details for Product anti-AXL Antibody No. ABIN965632, Supplier: Login to see
Antigen
  • JTK11
  • UFO
  • AI323647
  • Ark
  • Tyro7
  • Ufo
Alternatives
anti-Human AXL antibody for Western Blotting
Epitope
C-Term, pTyr698, pTyr702, pTyr703
37
27
15
14
14
14
14
12
9
6
6
5
5
5
4
4
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
188
64
52
3
Host
Rabbit
154
42
4
2
1
Clonality
Polyclonal
Conjugate
This AXL antibody is un-conjugated
10
9
9
8
7
6
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (IHC)
156
102
50
28
23
22
13
7
6
5
2
1
1
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human AXL(Tyrosine-protein kinase receptor UFO)
Alternative Name AXL (AXL Antibody Abstract)
Background AXL(Tyrosine-protein kinase receptor UFO) may function as a signal transducer between specific cell types of mesodermal origin. In case of filovirus infection, AXL seems to function as a cell entry factor. AXL is heterodimer and heterotetramer with GAS6. AXL is a single-pass type I membrane protein. It is highly expressed in metastatic colon tumors. And weakly expressed in normal colon tissue. AXL belongs to the protein kinase superfamily and Tyr protein kinase family and AXL/UFO subfamily. AXL contains 1 protein kinase domain.
Pathways RTK Signaling
Restrictions For Research Use only
Product cited in: Shimojima, Takada, Ebihara et al.: "Tyro3 family-mediated cell entry of Ebola and Marburg viruses." in: Journal of virology, Vol. 80, Issue 20, pp. 10109-16, 2006 (PubMed).

Lee, Strunk, Spritz: "A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes." in: Oncogene, Vol. 8, Issue 12, pp. 3403-10, 1993 (PubMed).

Craven, Xu, Weiner et al.: "Receptor tyrosine kinases expressed in metastatic colon cancer." in: International journal of cancer. Journal international du cancer, Vol. 60, Issue 6, pp. 791-7, 1995 (PubMed).

Partanen, Mäkelä, Alitalo et al.: "Putative tyrosine kinases expressed in K-562 human leukemia cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 22, pp. 8913-7, 1991 (PubMed).

Janssen, Schulz, Steenvoorden et al.: "A novel putative tyrosine kinase receptor with oncogenic potential." in: Oncogene, Vol. 6, Issue 11, pp. 2113-20, 1991 (PubMed).

OBryan, Frye, Cogswell et al.: "axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase." in: Molecular and cellular biology, Vol. 11, Issue 10, pp. 5016-31, 1991 (PubMed).

Background publications Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).