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Details for Product No. ABIN965635

BCL2-Associated Agonist of Cell Death (BAD) (pSer112) antibody

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Antigen
Synonyms BBC2, BCL2L8, Bbc2, AI325008, bad, fa01b12, wu:fa01b12, wu:fa96d04, BAD
Epitope
»Alternatives pSer112
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN965635
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human BAD around the phosphorylation site of serine 112 (H-S-SP-Y-P).
Specificity BAD (phospho-Ser112) phosphorylated at serine 112.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name BAD
Research Area Apoptosis/Necrosis
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Wang, Sun, Paller: "Inhibition of integrin-linked kinase/protein kinase B/Akt signaling: mechanism for ganglioside-induced apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 48, pp. 44504-11, 2001 (PubMed).

Rice, Washington, Schleman et al.: "Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells." in: Cancer research, Vol. 63, Issue 3, pp. 616-20, 2003 (PubMed).

Zhang, Zhang, Shacter: "Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75." in: Molecular and cellular biology, Vol. 24, Issue 14, pp. 6205-14, 2004 (PubMed).

Alternatives for antigen "BCL2-Associated Agonist of Cell Death (BAD)", type "Antibodies"
Hosts (398), (23), (4), (2)
Reactivities (362), (257), (213), (60), (37), (37), (24), (3), (2), (2)
Applications (243), (128), (123), (110), (83), (60), (26), (10), (8), (5), (4), (4), (3), (2), (2), (2)
Conjugates (11), (11), (11), (11), (11), (11), (11), (11), (11), (11), (11)
Epitopes (37), (33), (27), (22), (21), (20), (20), (19), (15), (13), (7), (6), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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