BAD antibody (BCL2-Associated Agonist of Cell Death)

Details for Product anti-BAD Antibody No. ABIN965639, Supplier: Log in to see
Antigen
  • bad
  • fa01b12
  • wu:fa01b12
  • wu:fa96d04
  • BAD
  • BBC2
  • BCL2L8
  • AI325008
  • Bbc2
  • BCL2-antagonist of cell death b
  • BCL2-associated agonist of cell death
  • badb
  • BAD
  • Bad
Alternatives
anti-Human BAD antibody for Immunofluorescence (fixed cells)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
765
430
264
19
15
8
5
4
3
2
2
1
1
1
1
1
1
Host
Rabbit
940
49
2
1
Clonality
Polyclonal
Conjugate
This BAD antibody is un-conjugated
65
64
64
58
58
58
6
6
6
6
6
6
6
6
6
6
6
Application
Immunohistochemistry (IHC)
522
450
396
279
114
79
51
29
13
11
6
5
4
3
2
1
1
1
Options
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Immunogen This antiserum was produced against synthesized non-phosphopeptide derived from human BAD around the phosphorylation site of serine 112 (H-S-SP-Y-P).
Specificity BAD (Ab-112) antibody detects endogenous levels of total BAD protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name BAD (BAD Antibody Abstract)
Pathways MAPK Signaling, PI3K-Akt Signaling, RTK Signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Zhang, Zhang, Shacter: "Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75." in: Molecular and cellular biology, Vol. 24, Issue 14, pp. 6205-14, 2004 (PubMed).

Rice, Washington, Schleman, Beard, Driggers, Ahnen: "Sulindac sulfide inhibits epidermal growth factor-induced phosphorylation of extracellular-regulated kinase 1/2 and Bad in human colon cancer cells." in: Cancer research, Vol. 63, Issue 3, pp. 616-20, 2003 (PubMed).

Wang, Sun, Paller: "Inhibition of integrin-linked kinase/protein kinase B/Akt signaling: mechanism for ganglioside-induced apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 48, pp. 44504-11, 2001 (PubMed).