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Catenin, beta (pThr41), (pSer45) antibody

Details for Product No. ABIN965661
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Antigen
Synonyms Bfc, Catnb, Mesc, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, CTNNB, MRD19, armadillo, CHBCAT, beta-catenin, ctnnb1
Epitope
pThr41, pSer45
(41), (41), (36), (33), (24), (21), (14), (14), (13), (12), (9), (7), (6), (5), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(305), (283), (279), (171), (156), (110), (4), (3), (2), (2)
Host
Rabbit
(300), (5), (2)
Conjugate
Un-conjugated
(14), (14), (14), (14), (14), (14), (14), (14), (14), (14), (14), (1), (1)
Application
Immunohistochemistry (IHC)
(166), (140), (70), (63), (47), (15), (6), (2), (1), (1)
Pubmed 3 references available
Quantity 100 µg
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Request Want additional data for this product?

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Catalog No. ABIN965661
385.00 $
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from humanCatenin around the phosphorylation site of threonine 41/serine 45 (A-T-TP-T-A-P-SP-L-S).
Specificity -Catenin (phospho-Thr41/Ser45) antibody detects endogenous levels of -Catenin only when phosphorylated at threonine 41/serine 45.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name beta-Catenin
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Liu, Li, Semenov et al.: "Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism." in: Cell, Vol. 108, Issue 6, pp. 837-47, 2002 (PubMed).

Provost, Yamamoto, Lizardi et al.: "Functional correlates of mutations in beta-catenin exon 3 phosphorylation sites." in: The Journal of biological chemistry, Vol. 278, Issue 34, pp. 31781-9, 2003 (PubMed).

Provost, McCabe, Stern et al.: "Functional correlates of mutation of the Asp32 and Gly34 residues of beta-catenin." in: Oncogene, Vol. 24, Issue 16, pp. 2667-76, 2005 (PubMed).

Validation Images
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