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BIM antibody

BCL2L11 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN965669
  • Target See all BIM (BCL2L11) Antibodies
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    Reactivity
    • 173
    • 101
    • 91
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 161
    • 9
    • 5
    • 1
    Rabbit
    Clonality
    • 147
    • 29
    Polyclonal
    Conjugate
    • 68
    • 15
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIM antibody is un-conjugated
    Application
    • 118
    • 60
    • 46
    • 28
    • 25
    • 22
    • 15
    • 14
    • 14
    • 13
    • 10
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificity
    BIM (Ab-69/65) antibody detects endogenous levels of total BIM protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    The antiserum was produced against synthesized non-phosphopeptide derived from mouse BIM around the phosphorylation site of serine 69 (P-A-SP-P-G).
    Top Product
    Discover our top product BCL2L11 Primary Antibody
  • Application Notes
    IHC: 1:50-1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Fukazawa, Noguchi, Masumi, Murakami, Uehara: "BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors." in: Molecular cancer therapeutics, Vol. 3, Issue 10, pp. 1281-8, (2004) (PubMed).

    Luciano, Jacquel, Colosetti, Herrant, Cagnol, Pages, Auberger: "Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function." in: Oncogene, Vol. 22, Issue 43, pp. 6785-93, (2003) (PubMed).

  • Target
    BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))
    Alternative Name
    BIM (BCL2L11 Products)
    Synonyms
    bim antibody, BAM antibody, BIM antibody, BOD antibody, 1500006F24Rik antibody, Bim antibody, Bod antibody, BimL antibody, BIMEL antibody, BCL2-like 11 antibody, BCL2 like 11 antibody, BCL2-like 11 (apoptosis facilitator) antibody, bcl2l11 antibody, BCL2L11 antibody, Bcl2l11 antibody
    Pathways
    PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity
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