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Details for Product No. ABIN965669

BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) antibody

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Antigen
Synonyms BAM, BIM, BOD, Bim, Bod, 1500006F24Rik, BimL, bim
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN965669
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized non-phosphopeptide derived from mouse BIM around the phosphorylation site of serine 69 (P-A-SP-P-G).
Specificity BIM (Ab-69/65) antibody detects endogenous levels of total BIM protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Name BIM
Application Notes IHC: 1:50-1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Luciano, Jacquel, Colosetti et al.: "Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function." in: Oncogene, Vol. 22, Issue 43, pp. 6785-93, 2003 (PubMed).

Fukazawa, Noguchi, Masumi et al.: "BimEL is an important determinant for induction of anoikis sensitivity by mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitors." in: Molecular cancer therapeutics, Vol. 3, Issue 10, pp. 1281-8, 2004 (PubMed).

Alternatives for antigen "BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11)", type "Antibodies"
Hosts (151), (15), (12), (7), (3)
Reactivities (168), (128), (106), (37), (36), (24), (2), (1), (1)
Applications (125), (56), (47), (40), (37), (32), (20), (19), (16), (5), (5), (3), (3), (3)
Conjugates (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4)
Epitopes (21), (15), (12), (12), (9), (8), (4), (4), (4), (4), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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