C-JUN antibody (Jun Proto-Oncogene) (pSer243)

Details for Product anti-JUN Antibody No. ABIN965714, Supplier: Log in to see
Antigen
  • BSK
  • BSK/DJNK
  • Bsk
  • CG5680
  • D-JNK
  • D-junk
  • DBSK/JNK
  • DJNK
  • DJNK/bsk
  • Dmel\\CG5680
  • JNK
  • JNK/SAPK
  • Jnk
  • Junk
  • SAPKa
  • c-Jun
  • dJNK
  • jnk
  • Jun
  • AP-1
  • JUN
  • B230310J22Rik
  • p39
  • Junc
  • c-jun
  • AP1
  • fj36h07
  • wu:fj36h07
  • zgc:65863
  • CG2275
  • D-Jun
  • D-jun
  • D-jun/Jra
  • DJUN
  • DJun
  • Djun
  • Dmel\\CG2275
  • JRA
  • V
  • cJun
  • d-JRA
  • d-Jun
  • d-jun
  • dAP-1
  • dJRA
  • dJUN
  • dJra
  • dJun
  • djun
  • dm-Jun
  • jra
  • jun
  • l(2)46Ef
  • l(2)IA109
  • l(2R)IA109
  • jun oncogene
  • basket
  • C-JUN protein
  • c-Jun protein
  • c-jun transcription factor
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39)
  • Jun oncogene
  • jun proto-oncogene
  • Jun-related antigen
  • jun
  • bsk
  • C-JUN
  • Cdk5r2
  • Jun
  • JUN
  • Jra
Alternatives
anti-Mouse (Murine) C-JUN antibody for Western Blotting
Epitope
pSer243
91
75
52
47
46
46
43
30
30
20
19
17
15
15
15
15
11
8
8
7
7
6
6
5
5
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
879
552
497
71
60
49
45
44
39
33
24
20
14
9
8
5
5
3
2
2
2
1
1
Host
Rabbit
766
129
4
2
1
Conjugate
This C-JUN antibody is un-conjugated
19
18
18
11
10
10
8
8
7
7
7
7
7
7
7
7
7
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
719
381
223
180
106
93
87
71
28
22
15
11
10
9
6
5
2
2
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human cJun around the phosphorylation site of serine 243 (P-L-SP-P-I).
Specificity C-Jun (phospho-Ser243) antibody detects endogenous levels of c-Jun only when phosphorylated at serine 243.
Alternative Name c-Jun (JUN Antibody Abstract)
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Dérijard, Hibi, Wu, Barrett, Su, Deng, Karin, Davis: "JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain." in: Cell, Vol. 76, Issue 6, pp. 1025-37, 1994 (PubMed).

Kyriakis, Banerjee, Nikolakaki, Dai, Rubie, Ahmad, Avruch, Woodgett: "The stress-activated protein kinase subfamily of c-Jun kinases." in: Nature, Vol. 369, Issue 6476, pp. 156-60, 1994 (PubMed).

Smeal, Binetruy, Mercola, Birrer, Karin: "Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73." in: Nature, Vol. 354, Issue 6353, pp. 494-6, 1992 (PubMed).

Binétruy, Smeal, Karin: "Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain." in: Nature, Vol. 351, Issue 6322, pp. 122-7, 1991 (PubMed).

Product cited in: Boyle, Smeal, Defize, Angel, Woodgett, Karin, Hunter: "Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity." in: Cell, Vol. 64, Issue 3, pp. 573-84, 1991 (PubMed).

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