Jun Proto-Oncogene (JUN) (pSer63) antibody

Details for Product No. ABIN965715
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Antigen
Synonyms p39, B230310J22Rik, AP1, AP-1, c-Jun, Junc, c-jun, Jun, JUN, fj36h07, zgc:65863, wu:fj36h07
Epitope
pSer63
(71), (60), (55), (45), (37), (37), (29), (19), (13), (10), (9), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(598), (418), (387), (154), (152), (150), (139), (10), (7), (6), (3), (3), (3), (3), (3), (2), (2), (2), (2)
Host
Rabbit
(555), (57), (2), (1), (1)
Conjugate
Un-conjugated
(12), (12), (12), (12), (12), (12), (12), (12), (12), (12), (12)
Application
Immunohistochemistry (IHC)
(467), (221), (180), (127), (119), (66), (49), (21), (19), (8), (8), (6), (2), (1), (1), (1)
Pubmed 4 references available
Catalog no. ABIN965715
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
Options
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human c-Jun around the phosphorylation site of serine 63 (L-T-SP-P-D).
Specificity C-Jun (phospho-Ser63) antibody detects endogenous levels of c-Jun only when phosphorylated at serine 63.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Alternative Name c-Jun
Research Area Immunology, Innate Immunity, Transcription Factors
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Hurd, Waldron, Rozengurt: "Protein kinase D complexes with C-Jun N-terminal kinase via activation loop phosphorylation and phosphorylates the C-Jun N-terminus." in: Oncogene, Vol. 21, Issue 14, pp. 2154-60, 2002 (PubMed).

Li, Feng, Porter: "JNK-dependent phosphorylation of c-Jun on serine 63 mediates nitric oxide-induced apoptosis of neuroblastoma cells." in: The Journal of biological chemistry, Vol. 279, Issue 6, pp. 4058-65, 2004 (PubMed).

Sevilla, Santos, Barcia et al.: "c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK)." in: Oncogene, Vol. 23, Issue 55, pp. 8950-8, 2004 (PubMed).

Wei, Jin, Schlisio et al.: "The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase." in: Cancer cell, Vol. 8, Issue 1, pp. 25-33, 2005 (PubMed).

Hosts (555), (57), (2), (1), (1)
Reactivities (598), (418), (387), (154), (152), (150), (139), (10), (7), (6), (3), (3), (3), (3), (3), (2), (2), (2), (2)
Applications (467), (221), (180), (127), (119), (66), (49), (21), (19), (8), (8), (6), (2), (1), (1), (1)
Conjugates (12), (12), (12), (12), (12), (12), (12), (12), (12), (12), (12)
Epitopes (71), (60), (55), (45), (37), (37), (29), (19), (13), (10), (9), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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