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C-JUN antibody (Jun Proto-Oncogene) (pSer73)

Details for Product anti-JUN Antibody No. ABIN965716, Supplier: Log in to see
Antigen
  • AP-1
  • AP1
  • B230310J22Rik
  • Bsk
  • BSK
  • BSK/DJNK
  • c-jun
  • c-Jun
  • CG2275
  • CG5680
  • cJun
  • D-JNK
  • d-JRA
  • d-jun
  • d-Jun
  • D-Jun
  • D-jun
  • D-jun/Jra
  • D-junk
  • dAP-1
  • DBSK/JNK
  • DJNK
  • dJNK
  • DJNK/bsk
  • dJRA
  • dJra
  • DJUN
  • DJun
  • djun
  • dJun
  • dJUN
  • Djun
  • dm-Jun
  • Dmel\\CG2275
  • Dmel\\CG5680
  • fj36h07
  • JNK
  • Jnk
  • jnk
  • JNK/SAPK
  • JRA
  • jra
  • jun
  • Jun
  • JUN
  • Junc
  • Junk
  • l(2)46Ef
  • l(2)IA109
  • l(2R)IA109
  • p39
  • SAPKa
  • V
  • wu:fj36h07
  • zgc:65863
Alternatives
anti-Mouse (Murine) C-JUN antibody for Western Blotting
Epitope
pSer73
77
73
60
42
41
41
40
34
23
20
20
19
13
13
13
13
12
11
8
8
8
8
8
6
6
6
5
5
5
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
803
439
394
42
36
31
22
17
17
12
12
9
5
5
4
3
2
2
2
1
Host
Rabbit
710
117
2
2
1
Conjugate
This C-JUN antibody is un-conjugated
18
18
18
11
10
10
8
8
7
7
7
7
7
7
7
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
641
380
202
130
105
79
75
73
28
22
11
11
8
6
4
3
2
1
1
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human c-Jun around the phosphorylation site of serine 73 (L-A-SP-P-E).
Specificity C-Jun (phospho-Ser73) antibody detects endogenous levels of c-Jun only when phosphorylated at serine 73.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Alternative Name c-Jun (JUN Antibody Abstract)
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways MAPK Signaling, RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Hook, Peeling: "Syphilis control--a continuing challenge." in: The New England journal of medicine, Vol. 351, Issue 2, pp. 122-4, 2004 (PubMed).

Sevilla, Santos, Barcia, Vega, Lazo: "c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK)." in: Oncogene, Vol. 23, Issue 55, pp. 8950-8, 2004 (PubMed).

Smeal, Binetruy, Mercola, Birrer, Karin: "Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73." in: Nature, Vol. 354, Issue 6353, pp. 494-6, 1992 (PubMed).

Background publications Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Dérijard, Hibi, Wu, Barrett, Su, Deng, Karin, Davis: "JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain." in: Cell, Vol. 76, Issue 6, pp. 1025-37, 1994 (PubMed).

Binétruy, Smeal, Karin: "Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain." in: Nature, Vol. 351, Issue 6322, pp. 122-7, 1991 (PubMed).