anti-C-JUN antibody (Jun Proto-Oncogene) (pSer73)

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Antigen
Synonyms
BSK, BSK/DJNK, Bsk, CG5680, D-JNK, D-junk, DBSK/JNK, DJNK, DJNK/bsk, Dmel\\CG5680, JNK, JNK/SAPK, Jnk, Junk, SAPKa, c-Jun, dJNK, jnk, Jun, AP-1, JUN, B230310J22Rik, p39, Junc, c-jun, AP1, fj36h07, wu: ... show more
BSK, BSK/DJNK, Bsk, CG5680, D-JNK, D-junk, DBSK/JNK, DJNK, DJNK/bsk, Dmel\\CG5680, JNK, JNK/SAPK, Jnk, Junk, SAPKa, c-Jun, dJNK, jnk, Jun, AP-1, JUN, B230310J22Rik, p39, Junc, c-jun, AP1, fj36h07, wu:fj36h07, zgc:65863, CG2275, D-Jun, D-jun, D-jun/Jra, DJUN, DJun, Djun, Dmel\\CG2275, JRA, V, cJun, d-JRA, d-Jun, d-jun, dAP-1, dJRA, dJUN, dJra, dJun, djun, dm-Jun, jra, jun, l(2)46Ef, l(2)IA109, l(2R)IA109 show less
Alternatives
Epitope
pSer73
(73), (51), (48), (43), (43), (43), (41), (33), (20), (19), (18), (15), (15), (13), (13), (13), (13), (11), (8), (8), (8), (8), (7), (7), (6), (6), (6), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(777), (422), (353), (37), (29), (24), (22), (15), (15), (12), (11), (8), (5), (5), (3), (2), (2), (2), (2), (1), (1)
Host
Rabbit
(704), (97), (3), (2)
Conjugate
This C-JUN antibody is un-conjugated
(15), (15), (15), (12), (9), (9), (9), (6), (6), (6), (6), (6), (6), (6), (6)
Application
Immunohistochemistry (IHC)
(630), (361), (204), (116), (103), (74), (74), (67), (23), (20), (11), (10), (8), (6), (6), (3), (2), (1), (1)
Pubmed 6 references available
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Quantity 100 μg
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human c-Jun around the phosphorylation site of serine 73 (L-A-SP-P-E).
Specificity C-Jun (phospho-Ser73) antibody detects endogenous levels of c-Jun only when phosphorylated at serine 73.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using nonphosphopeptide corresponding to the phosphorylation site.
Alternative Name c-Jun (JUN Antibody Abstract)
Research Area Immunology, Innate Immunity, Transcription Factors
Pathways MAPK Signaling, RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Sevilla, Santos, Barcia et al.: "c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK)." in: Oncogene, Vol. 23, Issue 55, pp. 8950-8, 2004 (PubMed).

Hook, Peeling: "Syphilis control--a continuing challenge." in: The New England journal of medicine, Vol. 351, Issue 2, pp. 122-4, 2004 (PubMed).

Smeal, Binetruy, Mercola et al.: "Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73." in: Nature, Vol. 354, Issue 6353, pp. 494-6, 1992 (PubMed).

Background publications Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Dérijard, Hibi, Wu et al.: "JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain." in: Cell, Vol. 76, Issue 6, pp. 1025-37, 1994 (PubMed).

Binétruy, Smeal, Karin: "Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain." in: Nature, Vol. 351, Issue 6322, pp. 122-7, 1991 (PubMed).

Catalog No. ABIN965716
$398.75
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