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CARD9 antibody (Caspase Recruitment Domain Family, Member 9) (N-Term)

Details for Product anti-CARD9 Antibody No. ABIN965748, Supplier: Log in to see
Antigen
  • CANDF2
  • card9
  • Gm782
  • hCARD9
Epitope
N-Term
16
15
9
5
2
2
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
66
12
7
Host
Rabbit
68
3
Clonality
Polyclonal
Conjugate
This CARD9 antibody is un-conjugated
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
53
33
21
13
12
11
9
6
3
1
1
Supplier
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Immunogen Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human CARD9(Caspase recruitment domain-containing protein 9)
Purification Purified by antigen-specific affinity chromatography.
Alternative Name CARD9 (CARD9 Antibody Abstract)
Background CARD9(Caspase recruitment domain-containing protein 9) is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Three alternatively spliced variants of this gene encoding distinct isoforms have been reported.
Research Area Apoptosis/Necrosis
Application Notes ELISA, Western blotting: 1µg/ml for 2hrs.
Restrictions For Research Use only
Format Liquid
Buffer This antibody is stored in PBS, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Bertin, Guo, Wang, Srinivasula, Jacobson, Poyet, Merriam, Du, Dyer, Robison, DiStefano, Alnemri: "CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41082-6, 2001

Wang, Guo, Huang, Ke, Poyet, Manji, Merriam, Glucksmann, DiStefano, Alnemri, Bertin: "Card10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa B." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21405-9, 2001