Caveolin 1, Caveolae Protein, 22kDa (CAV1) (pTyr14) antibody

Details for Product No. ABIN965752
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Antigen
Synonyms fc07c04, wu:fc07c04, Cav-1, bscl3, cav1, cav1a, cgl3, vip21, cav1b, caveolin-1, cav, mstp085, Caveolin-1, CAV1, cav-1, Cav, caveolin 1, BSCL3, CGL3, MSTP085, PPH3, VIP21
Epitope
pTyr14
(39), (32), (25), (7), (6), (6), (5), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(209), (123), (121), (23), (21), (16), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(182), (30), (13), (3)
Conjugate
Un-conjugated
(6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC)
(168), (56), (54), (44), (31), (26), (25), (20), (16), (6), (4), (1), (1), (1)
Pubmed 4 references available
Quantity 100 μg
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Catalog No. ABIN965752
398.75 $
Plus shipping costs $45.00

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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Caveolin-1 around the phosphorylation site of tyrosine 14 (H-L-YP-T-V).
Specificity Caveolin-1 (phospho-Tyr14) antibody detects endogenous levels of Caveolin-1 only when phosphorylated at tyrosine 14.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name Caveolin-1
Research Area Signaling
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Maggi, Biedi, Segat et al.: "IGF-I induces caveolin 1 tyrosine phosphorylation and translocation in the lipid rafts." in: Biochemical and biophysical research communications, Vol. 295, Issue 5, pp. 1085-9, 2002 (PubMed).

Fielding, Chau, Liu et al.: "Mechanism of platelet-derived growth factor-dependent caveolin-1 phosphorylation: relationship to sterol binding and the role of serine-80." in: Biochemistry, Vol. 43, Issue 9, pp. 2578-86, 2004 (PubMed).

Labrecque, Nyalendo, Langlois et al.: "Src-mediated tyrosine phosphorylation of caveolin-1 induces its association with membrane type 1 matrix metalloproteinase." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 52132-40, 2004 (PubMed).

Zhang, Wolf-Yadlin, Ross et al.: "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 9, pp. 1240-50, 2005 (PubMed).

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