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Caveolin 1, Caveolae Protein, 22kDa (CAV1) (pTyr14) antibody

Antigen

Caveolin 1, Caveolae Protein, 22kDa (CAV1)
Synonyms CAV, CGL3, BSCL3, VIP21, MSTP085, Cav, Cav-1, MGC187299, CAV1, fc07c04, wu:fc07c04, cav1a, cav1b, caveolin 1, cav, vip21, mstp085, MGC107940, Caveolin-1, cav1
Binding Site
Alternatives

pTyr14
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (IHC)
4 references available
Catalog no. ABIN965752
Quantity 100ug  (100ug/100ul.)  (Variants)
Price 385.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name Caveolin-1
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Caveolin-1 around the phosphorylation site of tyrosine 14 (H-L-YP-T-V).
Specificity Caveolin-1 (phospho-Tyr14) antibody detects endogenous levels of Caveolin-1 only when phosphorylated at tyrosine 14.

Application Details
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Application Notes WB: 1:500~1:1000.
Concentration 100ug/100ul.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative 0.02% Sodium Azide
Storage Store at -20°C/1 year.
Research Area Signaling
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Product Maggi, Biedi, Segat et al.: "IGF-I induces caveolin 1 tyrosine phosphorylation and translocation in the lipid rafts." in: Biochemical and biophysical research communications, Vol. 295, Issue 5, pp. 1085-9, 2002 (PubMed).

Fielding, Chau, Liu et al.: "Mechanism of platelet-derived growth factor-dependent caveolin-1 phosphorylation: relationship to sterol binding and the role of serine-80." in: Biochemistry, Vol. 43, Issue 9, pp. 2578-86, 2004 (PubMed).

Labrecque, Nyalendo, Langlois et al.: "Src-mediated tyrosine phosphorylation of caveolin-1 induces its association with membrane type 1 matrix metalloproteinase." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 52132-40, 2004 (PubMed).

Zhang, Wolf-Yadlin, Ross et al.: "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 9, pp. 1240-50, 2005 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Caveolin 1, Caveolae Protein, 22kDa (CAV1)", type "Antibodies"
Hosts Rabbit (92), Goat (9), Mouse (8)
Reactivities Human (93), Rat (Rattus) (68), Mouse (Murine) (62), Dog (Canine) (9), Pig (Porcine) (5), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Hamster (1), Rabbit (1)
Applications Western Blotting (WB) (66), Immunofluorescence (IF) (35), ELISA (29), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (25), Immunohistochemistry (IHC) (12), Immunocytochemistry (ICC) (8), Immunoprecipitation (IP) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Dot Blot (DB) (1), Dot Blot (Dot) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Biotin (2), PE,Cy5.5 (2), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pTyr14 (12), N-Term (3), Tyr14 (3), AA 1-104 (1), C-Term (1), Center (1), Internal Region (1), pTyr493 (1)