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Caveolin-1 antibody (Caveolin 1, Caveolae Protein, 22kDa) (pTyr14)

Details for Product anti-CAV1 Antibody No. ABIN965752, Supplier: Log in to see
Antigen
  • bscl3
  • BSCL3
  • Cav
  • cav
  • cav-1
  • Cav-1
  • cav1
  • CAV1
  • cav1a
  • cav1b
  • Caveolin-1
  • caveolin-1
  • caveolin 1
  • CGL3
  • cgl3
  • fc07c04
  • MSTP085
  • mstp085
  • PPH3
  • vip21
  • VIP21
  • wu:fc07c04
Epitope
pTyr14
46
31
28
22
11
8
7
5
5
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
282
145
131
28
27
19
10
10
9
8
5
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Host
Rabbit
194
75
34
3
Conjugate
This Caveolin-1 antibody is un-conjugated
10
6
5
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
Application
Immunohistochemistry (IHC)
233
87
87
73
65
59
49
35
10
5
5
2
2
2
Supplier
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Caveolin-1 around the phosphorylation site of tyrosine 14 (H-L-YP-T-V).
Specificity Caveolin-1 (phospho-Tyr14) antibody detects endogenous levels of Caveolin-1 only when phosphorylated at tyrosine 14.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name Caveolin-1 (CAV1 Antibody Abstract)
Research Area Signaling
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Zhang, Wolf-Yadlin, Ross, Pappin, Rush, Lauffenburger, White: "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 9, pp. 1240-50, 2005 (PubMed).

Labrecque, Nyalendo, Langlois, Durocher, Roghi, Murphy, Gingras, Béliveau: "Src-mediated tyrosine phosphorylation of caveolin-1 induces its association with membrane type 1 matrix metalloproteinase." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 52132-40, 2004 (PubMed).

Product cited in: Fielding, Chau, Liu, Spencer, Fielding: "Mechanism of platelet-derived growth factor-dependent caveolin-1 phosphorylation: relationship to sterol binding and the role of serine-80." in: Biochemistry, Vol. 43, Issue 9, pp. 2578-86, 2004 (PubMed).

Maggi, Biedi, Segat, Barbero, Panetta, Cordera: "IGF-I induces caveolin 1 tyrosine phosphorylation and translocation in the lipid rafts." in: Biochemical and biophysical research communications, Vol. 295, Issue 5, pp. 1085-9, 2002 (PubMed).