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CD4 antibody

CD4 Reactivity: Human FACS, IHC (fro) Host: Mouse Monoclonal B486 (EDU-2) unconjugated
Catalog No. ABIN965795
  • Target See all CD4 Antibodies
    CD4
    Reactivity
    • 355
    • 199
    • 113
    • 38
    • 24
    • 20
    • 19
    • 18
    • 15
    • 11
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    • 10
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    • 2
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    • 1
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    • 1
    Human
    Host
    • 328
    • 146
    • 108
    • 4
    • 2
    • 1
    • 1
    Mouse
    Clonality
    • 445
    • 138
    • 3
    Monoclonal
    Conjugate
    • 195
    • 65
    • 54
    • 46
    • 30
    • 12
    • 11
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    • 5
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    • 4
    • 4
    • 3
    • 3
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    • 1
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    This CD4 antibody is un-conjugated
    Application
    • 470
    • 193
    • 99
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    • 2
    • 1
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    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody reacts with a 55kD single chain transmembrane glycoprotien, CD4, expressed on T helper lymphocytes, dendritic cells, microglial cells, and cortical thymus cells. Characteristic of CD4 is its four extracellular immunoglobulin-like domains which help it bind to HLA class II molecules when CD4+ T cells interact with antigenpresenting cells or target cells. Another interesting aspect of the CD4 receptor is the fact that it also serves as the primary receptor for the HIV virus. This antibody was clustered at the 2nd International Leucocyte Typing Workshop.
    Purification
    Concentrated.
    Immunogen
    Human leucocytes
    Clone
    B486 (EDU-2)
    Isotype
    IgG2a
    Top Product
    Discover our top product CD4 Primary Antibody
  • Application Notes
    Immunohistochemistry: 1:50-1:100.(Frozen sections only)
    Flow cytometry: 1:150-1:300.
    Staining Procedure: This antibody can be used on frozen sections only. The antibody may be used at a dilution of 1:50-1:100 in IHC. The optimal conditions should be determined by the individual laboratory.
    Comment

    Recommended Positive Control: Tonsil, Thymus, Spleen

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.3 mg/ml.
    Buffer
    20 mM tris-borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing fetal bovine serum, BMC-6 carrier polysaccharides, carrier protein, pH 7.5
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Zosimova: "[Gas chromatographic detection of benzene, toluene and xylene in biological matter]." in: Sudebno-meditsinskaia ekspertiza, Vol. 29, Issue 3, pp. 37-8, (1986) (PubMed).

  • Target
    CD4
    Alternative Name
    CD4 (CD4 Products)
    Synonyms
    cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
    Gene ID
    920
    Pathways
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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