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Details for Product No. ABIN965831

Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer75) antibody

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Antigen
Synonyms CDC25A2, D9Ertd393e, cdc25A, sb:cb317, cdc25a2
Epitope
»Alternatives pSer75
Reactivity
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Host
»Alternatives Rabbit
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN965831
Quantity 100 µg
Price
385.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 7 Business Days
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human cdc25A around the phosphorylation site of serine 75 (M-G-SP-S-E).
Specificity Cdc25A (phospho-Ser75) antibody detects endogenous levels of cdc25A only when phosphorylated at serine 75.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name cdc25A
Research Area CD Antigens, Surface Receptors of Immune Cells, Cell Cycle, Cancer, Kinases/Phosphatases
Application Notes WB: 1:500~1:1000.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Storage -20 °C
Product cited in: Shimuta, Nakajo, Uto et al.: "Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition." in: The EMBO journal, Vol. 21, Issue 14, pp. 3694-703, 2002 (PubMed).

Jin, Shirogane, Xu et al.: "SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase." in: Genes & development, Vol. 17, Issue 24, pp. 3062-74, 2003 (PubMed).

Alternatives for antigen "Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A)", type "Antibodies"
Hosts (247), (34), (1)
Reactivities (278), (140), (139), (74), (62), (37), (12), (1), (1), (1)
Applications (206), (78), (70), (61), (49), (33), (5), (3), (2), (2), (2), (1), (1), (1), (1)
Conjugates (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (4)
Epitopes (31), (23), (22), (20), (15), (14), (11), (7), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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