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CDC42 antibody (AA 121-138)
CDC42
Reactivity: Human, Mouse, Rat, Cow
WB, ICC, IHC (p), IHC (fro)
Polyclonal
unconjugated
Product Details anti-CDC42 Antibody
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Target
See all CDC42 Antibodies
CDC42
(Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
Binding Specificity
All epitopes for CDC42 antibodies
AA 121-138
Reactivity
All reactivities for CDC42 antibodies
Human, Mouse, Rat, Cow
Host
Please inquire
Clonality
All clonalities for CDC42 antibodies
Polyclonal
Conjugate
All conjugates for CDC42 antibodies
This CDC42 antibody is un-conjugated
Application
All applications for CDC42 antibodies
Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
Immunogen
A synthetic peptide corresponding to a sequence at the middle region of human CDC42 (121-138aa), identical to the related mouse and rat sequence.
Top Product
Discover our top product CDC42 Primary Antibody
Alternatives
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Application Details
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Restrictions
For Research Use only
Handling
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Reconstitution
0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Preservative
Thimerosal (Merthiolate), Sodium azide
Storage
-20 °C
Target Details for CDC42
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Target
CDC42
(Cell Division Cycle 42 (GTP Binding Protein, 25kDa) (CDC42))
Alternative Name
CDC42 (CDC42 Products )
Synonyms
CDC42Hs antibody, G25K antibody, AI747189 antibody, AU018915 antibody, cdc42a antibody, wu:fb07d08 antibody, wu:fj62g06 antibody, zgc:63918 antibody, Xcdc42 antibody, cdc42hs antibody, g25k antibody, CDC42 antibody, CG12530 antibody, Cdc42Dm antibody, D-CDC42 antibody, D-Cdc42 antibody, D-cdc42 antibody, DCDC42 antibody, DCdc42 antibody, Dcdc42 antibody, Dm Cdc42 antibody, DmCDC42 antibody, Dmcdc42 antibody, Dmel\\CG12530 antibody, cdc42 antibody, cell division cycle 42 antibody, Cell division control protein 42 homolog antibody, cell division control protein 42 homolog antibody, cell division cycle 42 L homeolog antibody, CG12530 gene product from transcript CG12530-RC antibody, Rho family GTPase antibody, CDC42 antibody, Cdc42 antibody, cdc42 antibody, LOC100636735 antibody, LOC100637699 antibody, LOC100638834 antibody, cdc42.L antibody
Background
Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene.CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants.
Pathways
MAPK Signaling , Microtubule Dynamics , RTK Signaling , WNT Signaling , TCR Signaling , EGFR Signaling Pathway , Regulation of Actin Filament Polymerization , Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Maintenance of Protein Location , Skeletal Muscle Fiber Development , Signaling Events mediated by VEGFR1 and VEGFR2 , EGFR Downregulation , VEGF Signaling
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