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CHD3 antibody

CHD3 Reactivity: Human, Mouse WB, IHC, ELISA, IF, FACS Host: Mouse Monoclonal 2G4 unconjugated
Catalog No. ABIN965879
  • Target See all CHD3 Antibodies
    CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
    Reactivity
    • 30
    • 21
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 34
    • 13
    • 1
    Mouse
    Clonality
    • 33
    • 15
    Monoclonal
    Conjugate
    • 27
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHD3 antibody is un-conjugated
    Application
    • 23
    • 13
    • 13
    • 12
    • 11
    • 11
    • 9
    • 8
    • 8
    • 7
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human CHD3 expressed in E. Coli.
    Clone
    2G4
    Isotype
    IgG1
    Top Product
    Discover our top product CHD3 Primary Antibody
  • Application Notes
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Burd, Kinyamu, Miller, Archer: "UV radiation regulates Mi-2 through protein translation and stability." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34976-82, (2008) (PubMed).

    Goehler, Lalowski, Stelzl, Waelter, Stroedicke, Worm, Droege, Lindenberg, Knoblich, Haenig, Herbst, Suopanki, Scherzinger, Abraham, Bauer, Hasenbank, Fritzsche, Ludewig, Büssow, Buessow, Coleman et al.: "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. ..." in: Molecular cell, Vol. 15, Issue 6, pp. 853-65, (2004) (PubMed).

    Lepesheva, Virus, Waterman: "Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function." in: Biochemistry, Vol. 42, Issue 30, pp. 9091-101, (2003) (PubMed).

  • Target
    CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))
    Alternative Name
    CHD3 (CHD3 Products)
    Synonyms
    CG9594 antibody, CHD-3 antibody, CHD3 antibody, DmCHD3 antibody, Dmel\\CG9594 antibody, chd3 antibody, dCHD3 antibody, LOC568230 antibody, zfh antibody, mi-2a antibody, mi2-alpha antibody, Mi-2a antibody, Mi2-ALPHA antibody, ZFH antibody, 2600010P09Rik antibody, AF020312 antibody, Chd7 antibody, Prp7 antibody, Prp9-1 antibody, CG9594 gene product from transcript CG9594-RA antibody, chromodomain helicase DNA binding protein 3 antibody, chromodomain-helicase-DNA-binding protein 3 antibody, Chd3 antibody, CHD3 antibody, chd3 antibody, LOC100480350 antibody
    Background
    This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
    Synonyms: ZFH, Mi-2a, Mi2ALPHA, CHD3
    Molecular Weight
    226kDa
    Gene ID
    1107
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