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Keratin 7 (KRT7) antibody

Details for Product No. ABIN965903, Supplier: Log in to see
Antigen
  • CK7
  • D15Wsu77e
  • K2C7
  • K7
  • Krt2-7
  • KRT7
  • SCL
Reactivity
Human
477
133
65
8
7
6
5
5
3
2
1
1
1
Host
Mouse
329
173
3
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
26
17
11
10
9
9
7
7
7
7
7
7
7
7
7
7
7
7
2
2
2
2
2
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS), ELISA, Western Blotting (WB)
288
225
208
121
106
71
50
43
22
18
11
8
7
3
2
1
1
Supplier
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Immunogen Purified recombinant fragment of human CK7 expressed in E. Coli.
Clone 5D12
Isotype IgG1
Purification Ascitic fluid
Alternative Name CK7 (KRT7 Antibody Abstract)
Background CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants, however, not all variants have been fully described.
Synonyms: KRT7, cytokeratin 7
Molecular Weight 51kDa
Gene ID 3855
Application Notes Western Bloting: 1/500 - 1/2000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.
Restrictions For Research Use only
Format Liquid
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Product cited in: Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, 2006 (PubMed).

Bouwens: "Cytokeratins and cell differentiation in the pancreas." in: The Journal of pathology, Vol. 184, Issue 3, pp. 234-9, 1998 (PubMed).

Rosenberg, Fuchs, Le Beau, Eddy, Shows: "Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12." in: Cytogenetics and cell genetics, Vol. 57, Issue 1, pp. 33-8, 1991 (PubMed).