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Cofilin 1 (Non-Muscle) (CFL1) (pSer3) antibody

Details for Product No. ABIN965910, Supplier: Log in to see
Antigen
  • cfl1
  • xac1
  • xac2
  • cfl
  • cb86
  • sb:cb86
  • zgc:56501
  • wu:fb18a04
  • wu:fk77b03
  • 12/8
  • ADF
  • ADF/cofilin
  • Adf
  • CG4254
  • Cadf
  • D-cof
  • D61
  • Dmel\\CG4254
  • T8
  • Tsr
  • cofilin
  • cofilin/ADF
  • cofilin/actin depolymerizing factor homolog
  • l(2)03101
  • l(2)k03101
  • l(2)k05633
  • l(2)k13409
  • ntf
  • CFL
  • AA959946
  • Cof
  • CFL1
  • cofilin 1 (non-muscle)
  • twinstar
  • Cof1p
  • cofilin
  • cofilin 1 (non-muscle)-like
  • cofilin 1, non-muscle
  • COFILIN protein
  • Contrafreeloading
  • cfl1-a
  • cfl1
  • CFL1
  • tsr
  • COF1
  • TSTA_042790
  • Cfl1
  • LOC100341589
  • COFILIN
  • CFL
Alternatives
anti-Human Cofilin 1 (Non-Muscle) antibody for Immunocytochemistry
Epitope
pSer3
56
32
28
23
15
14
13
13
11
10
5
5
4
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
307
194
158
12
11
9
7
5
2
2
1
1
1
1
Host
Rabbit
242
61
4
Conjugate
Un-conjugated
12
11
11
8
7
7
4
4
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
221
129
99
65
61
41
35
25
17
6
5
4
2
2
1
Options
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human cofilin around the phosphorylation site of serine 3 (M-A-SP-G-V). 75 (M-G-SP-S-E).
Specificity Cofilin (phospho-Ser3) phosphorylated at serine 3.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name Cofilin (CFL1 Antibody Abstract)
Research Area Cancer, Cytoskeleton, Microfilaments
Pathways Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Kobayashi, Nishita, Mishima, Ohashi, Mizuno: "MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration." in: The EMBO journal, Vol. 25, Issue 4, pp. 713-26, 2006 (PubMed).

Background publications Wang, Shibasaki, Mizuno: "Calcium signal-induced cofilin dephosphorylation is mediated by Slingshot via calcineurin." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12683-9, 2005 (PubMed).