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GJA1 antibody (Gap Junction Protein, alpha 1, 43kDa) (pSer367)

Details for Product anti-GJA1 Antibody No. ABIN965917, Supplier: Log in to see
Antigen
  • cx43
  • gjal
  • oddd
  • dfnb38
  • connexin43
  • cx43a1
  • gja1
  • zfCx43.3
  • AU042049
  • AW546267
  • Cnx43
  • Cx43
  • Cx43alpha1
  • Gja-1
  • Npm1
  • AVSD3
  • CX43
  • DFNB38
  • GJAL
  • HLHS1
  • HSS
  • ODDD
  • connexin 43
  • gja1-A
  • Cnx46
  • Cx46
  • Gja-3
  • AI118175
  • Cnx32
  • Cx32
  • Gjb-1
  • gap junction protein, alpha 1, 43kDa
  • connexin 43
  • CONNEXIN 43 protein
  • connexin 43-like
  • gap junction protein, alpha 1
  • gap junction protein, alpha 3
  • gap junction protein, beta 1
  • gja1
  • cx43
  • CX43
  • CONNEXIN 43
  • LOC100359132
  • Gja1
  • GJA1
  • Gja3
  • Gjb1
Alternatives
anti-Mouse (Murine) GJA1 antibody for Immunohistochemistry (Frozen Sections)
Epitope
pSer367
66
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20
15
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8
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3
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2
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2
2
1
1
1
1
1
1
1
1
1
1
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1
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1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
257
195
175
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25
22
22
20
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17
10
10
7
7
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1
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Host
Rabbit
254
27
23
Conjugate
This GJA1 antibody is un-conjugated
5
5
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3
3
2
2
2
2
2
2
2
1
1
1
1
1
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Application
Immunohistochemistry (IHC)
239
120
104
73
43
19
14
13
12
7
7
5
2
2
Options
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human Connexin43 around the phosphorylation site of serine 367 (R-A-SP-S-R).
Specificity Connexin43 (phospho-Ser367) antibody detects endogenous levels of Connexin43 only when phosphorylated at serine 367.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Alternative Name Connexin 43 (GJA1 Antibody Abstract)
Research Area Extracellular Matrix, Cytoskeleton, Signaling
Pathways MAPK Signaling, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
Application Notes WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Product cited in: Matsushita, Kurihara, Watanabe, Okada, Sakai, Amano: "Alterations of phosphorylation state of connexin 43 during hypoxia and reoxygenation are associated with cardiac function." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 3, pp. 343-53, 2006 (PubMed).

Solan, Fry, TenBroek, Lampe: "Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation." in: Journal of cell science, Vol. 116, Issue Pt 11, pp. 2203-11, 2003 (PubMed).